Rabbit Polyclonal Phospho-Csk (S364) antibody (STJ90456)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Polyclonal Phospho-Csk (S364) antibody (STJ90456)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Csk (phospho Ser364) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

Expand

CSK antibody,|C SRC antibody|C SRC kinase antibody|C src Tyrosine Kinase antibody|C-SRC kinase antibody|c-src tyrosine kinase antibody|Csk A antibody|CSK antibody|CSK_HUMAN antibody|CYTOPLASMIC TYROSINE KINASE antibody|EC 2.7.10.2 antibody|MGC112926 antibody|MGC117393 antibody|MGC154049 antibody|P60 Src antibody|Protein tyrosine kinase CYL antibody|Protein-tyrosine kinase CYL antibody|Proto oncogene tyrosine protein kinase antibody|Tyrosine protein kinase CSK antibody|Tyrosine-protein kinase CSK antibody|zgc:154049 antibody|Anti-CSK antibody (ab744)
SCBT cat No: sc-166513|sc-286|sc-51580|sc-166560|sc-13074|sc-9897|

 

Name

Csk (phospho Ser364) Polyclonal Antibody

Catalogue No.

STJ90456

Reactivity

Human, Mouse, Rat

Specificity

Phospho-Csk (S364) Polyclonal Antibody detects endogenous levels of Csk protein only when phosphorylated at S364.

Immunogen

Synthesized phospho-peptide derived from Csk (phospho Ser364) at AA range 300-380

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

50 kDa

Formulation

Csk (phospho Ser364) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Csk (phospho Ser364) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Tyrosine-protein kinase CSK antibody, C-Src kinase antibody, Protein-tyrosine kinase CYL antibody

Database links

Human UniProt/Swiss-Prot:P41240;Mouse UniPort/Swiss-Prot: P41241;Rat UniProt/Swiss-Port: P32577;Human Entrez Gene: 1445;Mouse Entrez Gene: 12988;Rat Entrez Gene: Rn.2759

Protein names

Tyrosine-protein kinase CSK , C-Src kinase , Protein-tyrosine kinase CYL

Protein function

Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK. / ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. / Mg2+

Protein tissue specificity

Expressed in lung and macrophages.

Protein sequence and domain

The architecture of this protein is similar to that of Src-family kinases (SFKs) with one N-terminal SH3 domain, one SH2 domain, and a C-terminal kinase domain. / Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily. / Contains 1 protein kinase domain. / Contains 1 SH2 domain. / Contains 1 SH3 domain.

Protein post-translational modifications

Phosphorylated at Ser-364 by PKA, leading to increased activity. Autophosphorylated.

Protein cellular localization

Cytoplasm / Cell membrane

Research area

All research areas>Kinases and Phosphatases>Csk
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize Csk (phospho Ser364) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!