Rabbit Polyclonal Phospho-CTNNA1-S641 antibody (AP0273)

$99.00$259.00

Reactivity: Human,Mouse
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-CTNNA1-S641 antibody (AP0273)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CAP102 antibody;
Alpha E-catenin antibody|Cadherin associated protein 102kDa antibody|Cadherin associated protein antibody|Cadherin-associated protein antibody|CAP 102 antibody|CAP102 antibody|Catenin (cadherin associated protein) alpha 1 102kDa antibody|Catenin (cadherin associated protein), alpha 1, 102kDa antibody|Catenin alpha 1 antibody|Catenin alpha-1 antibody|CTNA1_HUMAN antibody|CTNNA 1 antibody|Ctnna1 antibody|FLJ36832 antibody|FLJ52416 antibody|NY REN 13 antigen antibody|OTTHUMP00000224141 antibody|OTTHUMP00000224147 antibody|Renal carcinoma antigen NY REN 13 antibody|Renal carcinoma antigen NY-REN-13 antibody|Anti-alpha 1 Catenin antibody [EP1793Y] (ab51032)

SCBT cat No: sc-47753|sc-1495|sc-9988|sc-7894|sc-101514|

Name

Rabbit Polyclonal Phospho-CTNNA1-S641 antibody

Catalogue No.

AP0273

Reactivity

Human, Mouse

Immunogen

A phospho specific peptide corresponding to residues surrounding S641 of human CTNNA1

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

100kDa

Formulation

Phospho-CTNNA1-S641 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CAP102 antibody;

Protein names

CAP102;

Protein function

Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.

Protein tissue specificity

Expressed ubiquitously in normal tissues.

Protein sequence and domain

Belongs to the vinculin/alpha-catenin family.

Protein post-translational modifications

Sumoylated.

Protein cellular localization

Isoform 1: Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Note=Found at cell-cell boundaries and probably at cell-matrix boundaries.; Isoform 3: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side .

Research area

<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Cell-Adhesion-Proteins/">Cell Adhesion Proteins</a>><a href="http://antibodyplus.com/product-tag/Catenin/">Catenin</a><br><a href="http://antibodyplus.com/product-tag/Cell-Adhesion-Proteins/"&gt; (View all antibody categories related to Cell Adhesion Proteins)</a>

Note

AntibodyPlus can customize Phospho-CTNNA1-S641 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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