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Rabbit Polyclonal Phospho-CTNNA1-S641 antibody (AP0273)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit Polyclonal Phospho-CTNNA1-S641 antibody.
Check alternative names for the antibodyExpand
Alpha E-catenin antibody|Cadherin associated protein 102kDa antibody|Cadherin associated protein antibody|Cadherin-associated protein antibody|CAP 102 antibody|CAP102 antibody|Catenin (cadherin associated protein) alpha 1 102kDa antibody|Catenin (cadherin associated protein), alpha 1, 102kDa antibody|Catenin alpha 1 antibody|Catenin alpha-1 antibody|CTNA1_HUMAN antibody|CTNNA 1 antibody|Ctnna1 antibody|FLJ36832 antibody|FLJ52416 antibody|NY REN 13 antigen antibody|OTTHUMP00000224141 antibody|OTTHUMP00000224147 antibody|Renal carcinoma antigen NY REN 13 antibody|Renal carcinoma antigen NY-REN-13 antibody|Anti-alpha 1 Catenin antibody [EP1793Y] (ab51032)
SCBT cat No: sc-47753|sc-1495|sc-9988|sc-7894|sc-101514|
Rabbit Polyclonal Phospho-CTNNA1-S641 antibody
|Catalogue No.|| |
A phospho specific peptide corresponding to residues surrounding S641 of human CTNNA1
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Phospho-CTNNA1-S641 antibody was tube-contained.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
Human UniProt/Swiss-Prot:<a href="http://www.uniprot.org/uniprot/P35221">P35221</a>
|Protein names|| |
|Protein function|| |
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
|Protein tissue specificity|| |
Expressed ubiquitously in normal tissues.
|Protein sequence and domain|| |
Belongs to the vinculin/alpha-catenin family.
|Protein post-translational modifications|| |
|Protein cellular localization|| |
Isoform 1: Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Note=Found at cell-cell boundaries and probably at cell-matrix boundaries.; Isoform 3: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side .
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Cell-Adhesion-Proteins/">Cell Adhesion Proteins</a>><a href="http://antibodyplus.com/product-tag/Catenin/">Catenin</a><br><a href="http://antibodyplus.com/product-tag/Cell-Adhesion-Proteins/"> (View all antibody categories related to Cell Adhesion Proteins)</a>
AntibodyPlus can customize Phospho-CTNNA1-S641 antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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