Rabbit Polyclonal Phospho-Cyclin C (S275) antibody (STJ90976)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Polyclonal Phospho-Cyclin C (S275) antibody (STJ90976)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Cyclin C (phospho Ser275) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

Expand

CCNC antibody,|ccnc antibody|CCNC_HUMAN antibody|CycC antibody|Cyclin C antibody|Cyclin-C antibody|hSRB11 antibody|OTTHUMP00000016897 antibody|SRB11 homolog antibody|Phospho anti-Cyclin C (S275) antibody (ab78868)
SCBT cat No: sc-1061|

 

Name

Cyclin C (phospho Ser275) Polyclonal Antibody

Catalogue No.

STJ90976

Reactivity

Human, Mouse, Rat

Specificity

Phospho-Cyclin C (S275) Polyclonal Antibody detects endogenous levels of Cyclin C protein only when phosphorylated at S275.

Immunogen

Synthesized phospho-peptide derived from Cyclin C (phospho Ser275) at AA range 210-290

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

37 kDa

Formulation

Cyclin C (phospho Ser275) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Cyclin C (phospho Ser275) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Cyclin-C antibody, SRB11 homolog antibody, hSRB11 antibody

Database links

Human UniProt/Swiss-Prot:P24863;Mouse UniPort/Swiss-Prot: Q62447;Rat UniProt/Swiss-Port: G3V738;Human Entrez Gene: 892;Mouse Entrez Gene: 51813;Rat Entrez Gene: Rn.106758

Protein names

Cyclin-C , SRB11 homolog , hSRB11

Protein function

Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.

Protein tissue specificity

Highest levels in pancreas. High levels in heart, liver, skeletal muscle and kidney. Low levels in brain.

Protein sequence and domain

Belongs to the cyclin family. Cyclin C subfamily. / Contains 1 cyclin N-terminal domain.

Protein cellular localization

Nucleus

Research area

All research areas>Cell Cycle Proteins>Cyclin
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize Cyclin C (phospho Ser275) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!