Rabbit Polyclonal Phospho-Cyclin C (S275) antibody (STJ90976)


Reactivity: Human, Mouse, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-Cyclin C (S275) antibody (STJ90976)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Cyclin C (phospho Ser275) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody


CCNC antibody,|ccnc antibody|CCNC_HUMAN antibody|CycC antibody|Cyclin C antibody|Cyclin-C antibody|hSRB11 antibody|OTTHUMP00000016897 antibody|SRB11 homolog antibody|Phospho anti-Cyclin C (S275) antibody (ab78868)
SCBT cat No: sc-1061|



Cyclin C (phospho Ser275) Polyclonal Antibody

Catalogue No.



Human, Mouse, Rat


Phospho-Cyclin C (S275) Polyclonal Antibody detects endogenous levels of Cyclin C protein only when phosphorylated at S275.


Synthesized phospho-peptide derived from Cyclin C (phospho Ser275) at AA range 210-290





Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;







Molecular weight

37 kDa


Cyclin C (phospho Ser275) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.


1 mg/ml


Cyclin C (phospho Ser275) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.


-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Cyclin-C antibody, SRB11 homolog antibody, hSRB11 antibody

Database links

Human UniProt/Swiss-Prot:P24863;Mouse UniPort/Swiss-Prot: Q62447;Rat UniProt/Swiss-Port: G3V738;Human Entrez Gene: 892;Mouse Entrez Gene: 51813;Rat Entrez Gene: Rn.106758

Protein names

Cyclin-C , SRB11 homolog , hSRB11

Protein function

Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.

Protein tissue specificity

Highest levels in pancreas. High levels in heart, liver, skeletal muscle and kidney. Low levels in brain.

Protein sequence and domain

Belongs to the cyclin family. Cyclin C subfamily. / Contains 1 cyclin N-terminal domain.

Protein cellular localization


Research area

All research areas>Cell Cycle Proteins>Cyclin
(View all antibody categories related to Cell Cycle Proteins)


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St John’s Laboratory Ltd.

Product type

Primary antibody


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