Rabbit Polyclonal Phospho-Cyclin E1 (T395) antibody (STJ90241)

$99.00$319.00

Reactivity: Human
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-Cyclin E1 (T395) antibody (STJ90241)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Cyclin E1 (phospho Thr395) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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CCNE1 antibody, CCNE antibody,|CCNE antibody|Ccne1 antibody|CCNE1_HUMAN antibody|cyclin E variant ex5del antibody|cyclin E variant ex7del antibody|Cyclin E1 antibody|Cyclin Es antibody|Cyclin Et antibody|CyclinE antibody|G1/S specific cyclin E antibody|G1/S-specific cyclin-E1 antibody|Anti-Cyclin E1 antibody [HE12] (ab3927)
SCBT cat No: sc-48420|sc-198|sc-377100|sc-20684|sc-248|sc-247|sc-481|sc-28351|

 

Name

Cyclin E1 (phospho Thr395) Polyclonal Antibody

Catalogue No.

STJ90241

Reactivity

Human

Specificity

Phospho-Cyclin E1 (T395) Polyclonal Antibody detects endogenous levels of Cyclin E1 protein only when phosphorylated at T395.

Immunogen

Synthesized phospho-peptide derived from Cyclin E1 (phospho Thr395) at AA range 330-410

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

48 kDa

Formulation

Cyclin E1 (phospho Thr395) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Cyclin E1 (phospho Thr395) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

G1/S-specific cyclin-E1 antibody

Database links

Human UniProt/Swiss-Prot:P24864;Mouse UniPort/Swiss-Prot: Q61457;Rat UniProt/Swiss-Port: B1WC54;Human Entrez Gene: 898;Mouse Entrez Gene: 12447;Rat Entrez Gene: Rn.15455

Protein names

G1/S-specific cyclin-E1

Protein function

Essential for the control of the cell cycle at the G1/S (start) transition.

Protein tissue specificity

Highly expressed in testis and placenta. Low levels in bronchial epithelial cells.

Protein sequence and domain

Belongs to the cyclin family. Cyclin E subfamily.

Protein post-translational modifications

Phosphorylation of both Thr-395 by GSK3 and Ser-399 by CDK2 creates a high affinity degron recognized by FBXW7, and accelerates degradation via the ubiquitin proteasome pathway. Phosphorylation at Thr-77 creates a low affinity degron also recognized by FBXW7. / Ubiquitinated by UHRF2; appears to occur independently of phosphorylation.

Protein cellular localization

Nucleus

Research area

All research areas>Cell Cycle Proteins>Cyclin
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize Cyclin E1 (phospho Thr395) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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