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Rabbit Polyclonal Phospho-Cyclin E1 (T395) antibody (STJ90241)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;
Recommended protocols: check protocols
Click or hover above images to see image description for Cyclin E1 (phospho Thr395) Polyclonal Antibody.
Check alternative names for the antibodyExpand
CCNE1 antibody, CCNE antibody,|CCNE antibody|Ccne1 antibody|CCNE1_HUMAN antibody|cyclin E variant ex5del antibody|cyclin E variant ex7del antibody|Cyclin E1 antibody|Cyclin Es antibody|Cyclin Et antibody|CyclinE antibody|G1/S specific cyclin E antibody|G1/S-specific cyclin-E1 antibody|Anti-Cyclin E1 antibody [HE12] (ab3927)
SCBT cat No: sc-48420|sc-198|sc-377100|sc-20684|sc-248|sc-247|sc-481|sc-28351|
Cyclin E1 (phospho Thr395) Polyclonal Antibody
|Catalogue No.|| |
Phospho-Cyclin E1 (T395) Polyclonal Antibody detects endogenous levels of Cyclin E1 protein only when phosphorylated at T395.
Synthesized phospho-peptide derived from Cyclin E1 (phospho Thr395) at AA range 330-410
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;
|Molecular weight|| |
Cyclin E1 (phospho Thr395) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Cyclin E1 (phospho Thr395) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
G1/S-specific cyclin-E1 antibody
|Protein names|| |
|Protein function|| |
Essential for the control of the cell cycle at the G1/S (start) transition.
|Protein tissue specificity|| |
Highly expressed in testis and placenta. Low levels in bronchial epithelial cells.
|Protein sequence and domain|| |
Belongs to the cyclin family. Cyclin E subfamily.
|Protein post-translational modifications|| |
Phosphorylation of both Thr-395 by GSK3 and Ser-399 by CDK2 creates a high affinity degron recognized by FBXW7, and accelerates degradation via the ubiquitin proteasome pathway. Phosphorylation at Thr-77 creates a low affinity degron also recognized by FBXW7. / Ubiquitinated by UHRF2; appears to occur independently of phosphorylation.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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