Rabbit Polyclonal Phospho-Dok-1 (Y362) antibody (STJ90244)


Reactivity: Human, Mouse, Rat
Applications: WB, IF, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-Dok-1 (Y362) antibody (STJ90244)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IF, ELISA

Recommended dilution: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Dok-1 (phospho Tyr362) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody


DOK1 antibody,|Docking protein 1 62kD antibody|Docking protein 1 antibody|DOK 1 antibody|DOK1 antibody|DOK1_HUMAN antibody|Downstream of tyrosine kinase 1 antibody|p62(dok) antibody|P62DOK antibody|pp62 antibody|Anti-DOK1 antibody (ab8112)
SCBT cat No: sc-135888|sc-6929|sc-46093|sc-6277|sc-6934|sc-135889|



Dok-1 (phospho Tyr362) Polyclonal Antibody

Catalogue No.



Human, Mouse, Rat


Phospho-Dok-1 (Y362) Polyclonal Antibody detects endogenous levels of Dok-1 protein only when phosphorylated at Y362.


Synthesized phospho-peptide derived from Dok-1 (phospho Tyr362) at AA range 300-380





Recommended dilution

WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000;







Molecular weight

55 kDa


Dok-1 (phospho Tyr362) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.


1 mg/ml


Dok-1 (phospho Tyr362) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.


-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Docking protein 1 antibody, Downstream of tyrosine kinase 1 antibody, p62antibody, dok antibody, antibody, pp62 antibody

Database links

Human UniProt/Swiss-Prot:Q99704;Mouse UniPort/Swiss-Prot: P97465;Rat UniProt/Swiss-Port: Q4QQV2;Human Entrez Gene: 1796;Mouse Entrez Gene: 13448;Rat Entrez Gene: Rn.117974

Protein names

Docking protein 1 , Downstream of tyrosine kinase 1 , p62, dok , , pp62

Protein function

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

Protein tissue specificity

Expressed in pancreas, heart, leukocyte and spleen. Expressed in both resting and activated peripheral blood T-cells. Expressed in breast cancer.

Protein sequence and domain

The PTB domain mediates receptor interaction. / Belongs to the DOK family. Type A subfamily. / Contains 1 IRS-type PTB domain. / Contains 1 PH domain.

Protein post-translational modifications

Constitutively tyrosine-phosphorylated. Phosphorylated by TEC (By similarity). Phosphorylated by LYN (By similarity). Phosphorylated on tyrosine residues by the insulin receptor kinase. Results in the negative regulation of the insulin signaling pathway. Phosphorylated on tyrosine residues by SRMS. / Isoform 3 contains a N-acetylmethionine at position 1.

Protein cellular localization

Cytoplasm / Nucleus / Cytoplasm > perinuclear region

Research area

All research areas>Signaling Intermediates>Dok
(View all antibody categories related to Signaling Intermediates)


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St John’s Laboratory Ltd.

Product type

Primary antibody


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