Rabbit Polyclonal Phospho-DREAM (S63) antibody (STJ91090)

$99.00$319.00

Reactivity: Human, Mouse
Applications: WB, IHC, IF, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-DREAM (S63) antibody (STJ91090)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for DREAM (phospho Ser63) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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KCNIP3 antibody, CSEN antibody, DREAM antibody, KCHIP3 antibody,|4933407H12Rik antibody|A type potassium channel modulatory protein 3 antibody|A-type potassium channel modulatory protein 3 antibody|AI413860 antibody|Calsenilin antibody|CSEN antibody|CSEN_HUMAN antibody|DRE antagonist modulator antibody|DRE-antagonist modulator antibody|DREAM antibody|EF hand transcription factor antibody|KCHIP 3 antibody|KChIP3 antibody|KCNIP 3 antibody|Kcnip3 antibody|Kv channel interacting protein 3 antibody|Kv channel-interacting protein 3 antibody|MGC18289 antibody|Potassium channel interacting protein 3 antibody|R74849 antibody|Anti-CSEN antibody (ab3474)
SCBT cat No: sc-166916|sc-9142|sc-9309|

 

Name

DREAM (phospho Ser63) Polyclonal Antibody

Catalogue No.

STJ91090

Reactivity

Human, Mouse

Specificity

Phospho-DREAM (S63) Polyclonal Antibody detects endogenous levels of DREAM protein only when phosphorylated at S63.

Immunogen

Synthesized phospho-peptide derived from DREAM (phospho Ser63) at AA range 40-120

Host

Rabbit

Applications

WB, IHC, IF, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

29 kDa

Formulation

DREAM (phospho Ser63) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

DREAM (phospho Ser63) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Calsenilin antibody, A-type potassium channel modulatory protein 3 antibody, DRE-antagonist modulator antibody, DREAM antibody, Kv channel-interacting protein 3 antibody, KChIP3 antibody

Database links

Human UniProt/Swiss-Prot:Q9Y2W7;Mouse UniPort/Swiss-Prot: Q9QXT8;Rat UniProt/Swiss-Port: Q9JM47;Human Entrez Gene: 30818;Mouse Entrez Gene: 56461;Rat Entrez Gene: Rn.74239

Protein names

Calsenilin , A-type potassium channel modulatory protein 3 , DRE-antagonist modulator , DREAM , Kv channel-interacting protein 3 , KChIP3

Protein function

Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity). / Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels, such as KCND2/Kv4.2 and KCND3/Kv4.3. Modulates channel expression at the cell membrane, gating characteristics, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. / May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of beta-amyloid formation.

Protein tissue specificity

Highly expressed in brain. Widely expressed at lower levels. Expression levels are elevated in brain cortex regions affected by Alzheimer disease.

Protein sequence and domain

Belongs to the recoverin family. / Contains 4 EF-hand domains.

Protein post-translational modifications

Palmitoylated. Palmitoylation enhances association with the plasma membrane (By similarity). / Proteolytically cleaved by caspase-3. / Phosphorylation at Ser-63 inhibits cleavage by CASP3.

Protein cellular localization

Cytoplasm / Cell membrane / Lipid-anchor / Endoplasmic reticulum / Golgi apparatus / Nucleus

Note

AntibodyPlus can customize DREAM (phospho Ser63) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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