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Rabbit Polyclonal Phospho-DREAM (S63) antibody (STJ91090)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, IF, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
KCNIP3 antibody, CSEN antibody, DREAM antibody, KCHIP3 antibody,|4933407H12Rik antibody|A type potassium channel modulatory protein 3 antibody|A-type potassium channel modulatory protein 3 antibody|AI413860 antibody|Calsenilin antibody|CSEN antibody|CSEN_HUMAN antibody|DRE antagonist modulator antibody|DRE-antagonist modulator antibody|DREAM antibody|EF hand transcription factor antibody|KCHIP 3 antibody|KChIP3 antibody|KCNIP 3 antibody|Kcnip3 antibody|Kv channel interacting protein 3 antibody|Kv channel-interacting protein 3 antibody|MGC18289 antibody|Potassium channel interacting protein 3 antibody|R74849 antibody|Anti-CSEN antibody (ab3474)
SCBT cat No: sc-166916|sc-9142|sc-9309|
DREAM (phospho Ser63) Polyclonal Antibody
|Catalogue No.|| |
Phospho-DREAM (S63) Polyclonal Antibody detects endogenous levels of DREAM protein only when phosphorylated at S63.
Synthesized phospho-peptide derived from DREAM (phospho Ser63) at AA range 40-120
WB, IHC, IF, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;
|Molecular weight|| |
DREAM (phospho Ser63) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
DREAM (phospho Ser63) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Calsenilin antibody, A-type potassium channel modulatory protein 3 antibody, DRE-antagonist modulator antibody, DREAM antibody, Kv channel-interacting protein 3 antibody, KChIP3 antibody
|Protein names|| |
Calsenilin , A-type potassium channel modulatory protein 3 , DRE-antagonist modulator , DREAM , Kv channel-interacting protein 3 , KChIP3
|Protein function|| |
Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity). / Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels, such as KCND2/Kv4.2 and KCND3/Kv4.3. Modulates channel expression at the cell membrane, gating characteristics, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. / May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of beta-amyloid formation.
|Protein tissue specificity|| |
Highly expressed in brain. Widely expressed at lower levels. Expression levels are elevated in brain cortex regions affected by Alzheimer disease.
|Protein sequence and domain|| |
Belongs to the recoverin family. / Contains 4 EF-hand domains.
|Protein post-translational modifications|| |
Palmitoylated. Palmitoylation enhances association with the plasma membrane (By similarity). / Proteolytically cleaved by caspase-3. / Phosphorylation at Ser-63 inhibits cleavage by CASP3.
|Protein cellular localization|| |
Cytoplasm / Cell membrane / Lipid-anchor / Endoplasmic reticulum / Golgi apparatus / Nucleus
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St John’s Laboratory Ltd.
|Product type|| |
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