Rabbit Polyclonal Phospho-EFNB2-Y316 antibody (AP0338)

$99.00$259.00

Reactivity: Human,Mouse
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-EFNB2-Y316 antibody (AP0338)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit Polyclonal Phospho-EFNB2-Y316 antibody.

Alternative names:

Check alternative names for the antibody

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HTKL antibody; EPLG5 antibody; Htk-L antibody; LERK5 antibody;
EFN B2 antibody|MGC126226 antibody|MGC126227 antibody|MGC126228 antibody|OTTMUSP00000024973 antibody|Anti-Ephrin B2 antibody [EPR10072(B)] (ab150411)

SCBT cat No: sc-19227|sc-398735|sc-15397|sc-1010|

Name

Rabbit Polyclonal Phospho-EFNB2-Y316 antibody

Catalogue No.

AP0338

Reactivity

Human, Mouse

Immunogen

A phospho specific peptide corresponding to residues surrounding Y316 of human EFNB2

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

37kDa

Formulation

Phospho-EFNB2-Y316 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HTKL antibody; EPLG5 antibody; Htk-L antibody; LERK5 antibody;

Protein names

HTKL; EPLG5; Htk-L; LERK5;

Protein function

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.; (Microbial infection) Acts as a receptor for Hendra virus and Nipah virus.

Protein tissue specificity

Lung and kidney.

Protein sequence and domain

Belongs to the ephrin family.; Contains 1 ephrin RBD (ephrin receptor-binding) domain.

Protein post-translational modifications

Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Background

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.

Research area

<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Growth-Factors-and-Hormones/">Growth Factors and Hormones</a>><a href="http://antibodyplus.com/product-tag/Ephrin/">Ephrin</a><br><a href="http://antibodyplus.com/product-tag/Growth-Factors-and-Hormones/"&gt; (View all antibody categories related to Growth Factors and Hormones)</a>

Note

AntibodyPlus can customize Phospho-EFNB2-Y316 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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