Rabbit Polyclonal Phospho-EIF4B-S422 antibody (AP0278)

$99.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-EIF4B-S422 antibody (AP0278)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit Polyclonal Phospho-EIF4B-S422 antibody.

Alternative names:

Check alternative names for the antibody

Expand

EIF-4B antibody; PRO1843 antibody;
2310046H11Rik antibody|AL024095 antibody|C85189 antibody|EIF 4B antibody|eIF-4B antibody|EIF4B antibody|Eukaryotic initiation factor 4B antibody|Eukaryotic translation initiation factor 4B antibody|IF4B_HUMAN antibody|PRO1843 antibody|Phospho anti-eIF4B (S422) antibody (ab59300)

SCBT cat No: sc-390912|sc-82586|sc-82587|sc-376062|sc-271480|

Name

Rabbit Polyclonal Phospho-EIF4B-S422 antibody

Catalogue No.

AP0278

Reactivity

Human, Mouse

Immunogen

A phospho specific peptide corresponding to residues surrounding S422 of human EIF4B

Host

Rabbit

Applications

WB, IHC

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

80kDa

Formulation

Phospho-EIF4B-S422 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

EIF-4B antibody; PRO1843 antibody;

Protein names

EIF-4B; PRO1843;

Protein function

Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

Protein sequence and domain

Contains 1 RRM (RNA recognition motif) domain.

Protein post-translational modifications

Phosphorylated at Ser-422 by RPS6KA1 and RPS6KB1; phosphorylation enhances the affinity of EIF4B for the EIF3 complex.

Research area

<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Signaling-Intermediates/">Signaling Intermediates</a>><a href="http://antibodyplus.com/product-tag/eIF4B/">eIF4B</a><br><a href="http://antibodyplus.com/product-tag/Signaling-Intermediates/"&gt; (View all antibody categories related to Signaling Intermediates)</a>

Note

AntibodyPlus can customize Phospho-EIF4B-S422 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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