Rabbit Polyclonal Phospho-EIF4E-S209 antibody (AP0228)

$99.00$259.00

Reactivity: Human
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-EIF4E-S209 antibody (AP0228)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000
IHC 1:50 – 1:100
IF 1:100 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

CBP antibody; EIF4F antibody; AUTS19 antibody; EIF4E1 antibody; EIF4EL1 antibody;
AUTS19 antibody|CBP antibody|eIF 4E antibody|eIF 4F 25 kDa subunit antibody|EIF 4F antibody|eIF-4E antibody|eIF-4F 25 kDa subunit antibody|eIF4E antibody|EIF4E1 antibody|EIF4EL1 antibody|EIF4F antibody|Eukaryotic translation initiation factor 4 E antibody|Eukaryotic translation initiation factor 4E antibody|Eukaryotic translation initiation factor 4E like 1 antibody|IF4E_HUMAN antibody|Messanger RNA Cap Binding Protein eIF 4E antibody|MGC111573 antibody|mRNA cap binding protein antibody|mRNA cap-binding protein antibody|Phospho anti-eIF4E (S209) antibody [EP2151Y] (ab76256)

SCBT cat No: sc-271480|sc-6968|sc-514875|sc-13963|sc-9976|sc-100731|

Name

Rabbit Polyclonal Phospho-EIF4E-S209 antibody

Catalogue No.

AP0228

Reactivity

Human

Immunogen

A phospho specific peptide corresponding to residues surrounding S209 of human EIF4E

Host

Rabbit

Applications

WB, IHC, IF

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

25kDa

Formulation

Phospho-EIF4E-S209 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CBP antibody; EIF4F antibody; AUTS19 antibody; EIF4E1 antibody; EIF4EL1 antibody;

Protein names

CBP; EIF4F; AUTS19; EIF4E1; EIF4EL1;

Protein function

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.

Protein sequence and domain

Belongs to the eukaryotic initiation factor 4E family.

Protein post-translational modifications

Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the eIF4F complex.

Protein cellular localization

Cytoplasm, P-body . Cytoplasm .

Background

The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of cellular mRNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the mRNA. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. Three transcript variants encoding different isoforms have been found for this gene.

Research area

<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Signaling-Intermediates/">Signaling Intermediates</a>><a href="http://antibodyplus.com/product-tag/eIF/">eIF</a><br><a href="http://antibodyplus.com/product-tag/Signaling-Intermediates/"&gt; (View all antibody categories related to Signaling Intermediates)</a>

Note

AntibodyPlus can customize Phospho-EIF4E-S209 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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