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Rabbit Polyclonal Phospho-Ephrin-B1 (Y317) antibody (STJ90516)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:20000;
Recommended protocols: check protocols
Click or hover above images to see image description for Ephrin-B1 (phospho Tyr317) Polyclonal Antibody.
Check alternative names for the antibodyExpand
EFNB1 antibody, EFL3 antibody, EPLG2 antibody, LERK2 antibody,|CFND antibody|MGC8782 antibody|Phospho anti-Ephrin B1 (Y331) antibody (ab30563)
SCBT cat No: sc-1011|sc-515264|sc-20723|sc-910|
Ephrin-B1 (phospho Tyr317) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-Ephrin-B1 (Y317) Polyclonal Antibody detects endogenous levels of Ephrin-B1 protein only when phosphorylated at Y317.
Synthesized phospho-peptide derived from Ephrin-B1 (phospho Tyr317) at AA range 260-340
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:20000;
|Molecular weight|| |
Ephrin-B1 (phospho Tyr317) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Ephrin-B1 (phospho Tyr317) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Ephrin-B1 antibody, EFL-3 antibody, ELK ligand antibody, ELK-L antibody, EPH-related receptor tyrosine kinase ligand 2 antibody, LERK-2 antibody
|Protein names|| |
Ephrin-B1 , EFL-3 , ELK ligand , ELK-L , EPH-related receptor tyrosine kinase ligand 2 , LERK-2
|Protein function|| |
Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). / Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to the receptor tyrosine kinases EPHB3 (preferred), EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).
|Protein tissue specificity|| |
Heart, placenta, lung, liver, skeletal muscle, kidney, pancreas.
|Involvement in disease|| |
Craniofrontonasal syndrome (CFNS) [MIM:304110]: X-linked inherited syndrome characterized by hypertelorism, coronal synostosis with brachycephaly, downslanting palpebral fissures, clefting of the nasal tip, joint anomalies, longitudinally grooved fingernails and other digital anomalies. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the ephrin family. / Contains 1 ephrin RBD (ephrin receptor-binding) domain.
|Protein post-translational modifications|| |
Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein
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St John’s Laboratory Ltd.
|Product type|| |
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