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Rabbit Polyclonal Phospho-ERbeta (S105) antibody (STJ90713)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IF, ELISA
Recommended dilution: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:5000;
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
ESR2 antibody, ESTRB antibody, NR3A2 antibody,|Atherosclerosis, susceptibility to, included antibody|DKFZp686N23123 antibody|ER Alpha antibody|ER antibody|ER Beta antibody|ER-alpha antibody|ER[a] antibody|ER[b] antibody|Era antibody|ERalpha antibody|Erb antibody|Erb2 antibody|ERbeta antibody|ESR antibody|ESR BETA antibody|ESR1 antibody|ESR1_HUMAN antibody|ESR2 antibody|ESRA antibody|ESRB antibody|Estr antibody|Estra antibody|Estradiol Receptor alpha antibody|Estradiol receptor antibody|Estradiol Receptor beta antibody|ESTRB antibody|Estrogen receptor 1 (alpha) antibody|Estrogen Receptor 1 antibody|Estrogen receptor 2 (ER beta) antibody|Estrogen Receptor 2 antibody|Estrogen receptor 2 ER beta antibody|Estrogen receptor alpha antibody|Estrogen receptor antibody|Estrogen receptor beta 4 antibody|Estrogen resistance, included antibody|HDL cholesterol, augmented response of, to hormone replacement, included antibody|Myocardial infarction, susceptibility to, included antibody|NR3A1 antibody|NR3A2 antibody|Nuclear receptor subfamily 3 group A member 1 antibody|Nuclear receptor subfamily 3 group A member 2 antibody|OTTHUMP00000017718 antibody|OTTHUMP00000017719 antibody|RNESTROR antibody|Anti-Estrogen Receptor antibody (ab53572)
SCBT cat No: sc-53494|sc-390243|sc-373853|sc-8974|sc-6822|sc-6820|sc-6821|
ERbeta (phospho Ser105) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-ERbeta (S105) Polyclonal Antibody detects endogenous levels of ERbeta protein only when phosphorylated at S105.
Synthesized phospho-peptide derived from ERbeta (phospho Ser105) at AA range 40-120
WB, IF, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:5000;
|Molecular weight|| |
ERbeta (phospho Ser105) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ERbeta (phospho Ser105) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Estrogen receptor beta antibody, ER-beta antibody, Nuclear receptor subfamily 3 group A member 2 antibody
|Protein names|| |
Estrogen receptor beta , ER-beta , Nuclear receptor subfamily 3 group A member 2
|Protein function|| |
Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner . Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
|Protein tissue specificity|| |
Isoform 1 is expressed in testis and ovary, and at a lower level in heart, brain, placenta, liver, skeletal muscle, spleen, thymus, prostate, colon, bone marrow, mammary gland and uterus. Also found in uterine bone, breast, and ovarian tumor cell lines, but not in colon and liver tumors. Isoform 2 is expressed in spleen, thymus, testis and ovary and at a lower level in skeletal muscle, prostate, colon, small intestine, leukocytes, bone marrow, mammary gland and uterus. Isoform 4 is found in testis. Isoform 5 is expressed in testis, and at a lower level in spleen, thymus, ovary, mammary gland and uterus. Isoform 6 is expressed in testis, placenta, skeletal muscle, spleen and leukocytes, and at a lower level in heart, lung, liver, kidney, pancreas, thymus, prostate, colon, small intestine, bone marrow, mammary gland and uterus. Not expressed in brain.
|Protein sequence and domain|| |
Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain. / Belongs to the nuclear hormone receptor family. NR3 subfamily. / Contains 1 nuclear receptor DNA-binding domain.
|Protein post-translational modifications|| |
Phosphorylation at Ser-87 and Ser-105 recruits NCOA1.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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