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Rabbit Polyclonal Phospho-ERK 8 (T175/Y177) antibody (STJ90517)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
Recommended protocols: check protocols
Click or hover above images to see image description for ERK 8 (phospho Thr175/Y177) Polyclonal Antibody.
Check alternative names for the antibodyExpand
MAPK15 antibody, ERK7 antibody, ERK8 antibody,|ERK-7 antibody|ERK-8 antibody|ERK7 antibody|ERK8 antibody|Extracellular regulated kinase 8 delta antibody|Extracellular signal regulated kinase 8 antibody|Extracellular signal-regulated kinase 7 antibody|Extracellular signal-regulated kinase 8 antibody|MAP kinase 15 antibody|MAPK 15 antibody|Mapk15 antibody|Mitogen activated protein kinase 15 antibody|Mitogen-activated protein kinase 15 antibody|MK15_HUMAN antibody|Anti-MAPK15 antibody (ab137619)
SCBT cat No: sc-86723|
ERK 8 (phospho Thr175/Y177) Polyclonal Antibody
|Catalogue No.|| |
Phospho-ERK 8 (T175/Y177) Polyclonal Antibody detects endogenous levels of ERK 8 protein only when phosphorylated at T175/Y177.
Synthesized phospho-peptide derived from ERK 8 (phospho Thr175/Y177) at AA range 110-190
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
|Molecular weight|| |
ERK 8 (phospho Thr175/Y177) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ERK 8 (phospho Thr175/Y177) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Mitogen-activated protein kinase 15 antibody, MAP kinase 15 antibody, MAPK 15 antibody, Extracellular signal-regulated kinase 7 antibody, ERK-7 antibody, Extracellular signal-regulated kinase 8 antibody, ERK-8 antibody
|Protein names|| |
Mitogen-activated protein kinase 15 , MAP kinase 15 , MAPK 15 , Extracellular signal-regulated kinase 7 , ERK-7 , Extracellular signal-regulated kinase 8 , ERK-8
|Protein function|| |
In vitro, phosphorylates MBP. / ATP + a protein = ADP + a phosphoprotein. / Activated by threonine and tyrosine phosphorylation. Inhibited by dual specificity phosphatases, such as DUSP1 (By similarity).
|Protein tissue specificity|| |
Widely expressed with a maximal expression in lung and kidney.
|Protein sequence and domain|| |
The N-terminal region (1-20) is the minimal region necessary for ubiquitination and further proteasomal degradation. / The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases. / Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. / Contains 1 protein kinase domain.
|Protein post-translational modifications|| |
Dually phosphorylated on Thr-175 and Tyr-177, which activates the enzyme. Autophosphorylated on threonine and tyrosine residues in vitro. / Ubiquitinated. Ubiquitination may allow its tight kinase activity regulation and rapid turnover. May be ubiquitinated by a SCF E3 ligase (By similarity).
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St John’s Laboratory Ltd.
|Product type|| |
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