Rabbit Polyclonal Phospho-ERK 8 (T175/Y177) antibody (STJ90517)

$99.00$319.00

Reactivity: Human, Mouse
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-ERK 8 (T175/Y177) antibody (STJ90517)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for ERK 8 (phospho Thr175/Y177) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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MAPK15 antibody, ERK7 antibody, ERK8 antibody,|ERK-7 antibody|ERK-8 antibody|ERK7 antibody|ERK8 antibody|Extracellular regulated kinase 8 delta antibody|Extracellular signal regulated kinase 8 antibody|Extracellular signal-regulated kinase 7 antibody|Extracellular signal-regulated kinase 8 antibody|MAP kinase 15 antibody|MAPK 15 antibody|Mapk15 antibody|Mitogen activated protein kinase 15 antibody|Mitogen-activated protein kinase 15 antibody|MK15_HUMAN antibody|Anti-MAPK15 antibody (ab137619)
SCBT cat No: sc-86723|

 

Name

ERK 8 (phospho Thr175/Y177) Polyclonal Antibody

Catalogue No.

STJ90517

Reactivity

Human, Mouse

Specificity

Phospho-ERK 8 (T175/Y177) Polyclonal Antibody detects endogenous levels of ERK 8 protein only when phosphorylated at T175/Y177.

Immunogen

Synthesized phospho-peptide derived from ERK 8 (phospho Thr175/Y177) at AA range 110-190

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

60 kDa

Formulation

ERK 8 (phospho Thr175/Y177) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

ERK 8 (phospho Thr175/Y177) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Mitogen-activated protein kinase 15 antibody, MAP kinase 15 antibody, MAPK 15 antibody, Extracellular signal-regulated kinase 7 antibody, ERK-7 antibody, Extracellular signal-regulated kinase 8 antibody, ERK-8 antibody

Database links

Human UniProt/Swiss-Prot:Q8TD08;Mouse UniPort/Swiss-Prot: Q80Y86;Rat UniProt/Swiss-Port: Q9Z2A6;Human Entrez Gene: 225689;Mouse Entrez Gene: 332110;Rat Entrez Gene: Rn.42898

Protein names

Mitogen-activated protein kinase 15 , MAP kinase 15 , MAPK 15 , Extracellular signal-regulated kinase 7 , ERK-7 , Extracellular signal-regulated kinase 8 , ERK-8

Protein function

In vitro, phosphorylates MBP. / ATP + a protein = ADP + a phosphoprotein. / Activated by threonine and tyrosine phosphorylation. Inhibited by dual specificity phosphatases, such as DUSP1 (By similarity).

Protein tissue specificity

Widely expressed with a maximal expression in lung and kidney.

Protein sequence and domain

The N-terminal region (1-20) is the minimal region necessary for ubiquitination and further proteasomal degradation. / The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases. / Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. / Contains 1 protein kinase domain.

Protein post-translational modifications

Dually phosphorylated on Thr-175 and Tyr-177, which activates the enzyme. Autophosphorylated on threonine and tyrosine residues in vitro. / Ubiquitinated. Ubiquitination may allow its tight kinase activity regulation and rapid turnover. May be ubiquitinated by a SCF E3 ligase (By similarity).

Research area

All research areas>Kinases and Phosphatases>ERK
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize ERK 8 (phospho Thr175/Y177) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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