Rabbit Polyclonal Phospho-Gab 1 (Y627) antibody (STJ90278)

$99.00$319.00

Reactivity: Human, Mouse, Monkey
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-Gab 1 (Y627) antibody (STJ90278)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Gab 1 (phospho Tyr627) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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GAB1 antibody,|Gab 1 antibody|GAB1 antibody|GAB1_HUMAN antibody|GRB 2 associated binder 1 antibody|GRB 2 associated binding protein 1 antibody|GRB2 associated binding protein 1 isoform a antibody|GRB2 associated binding protein 1 isoform b antibody|GRB2-associated binder 1 antibody|GRB2-associated-binding protein 1 antibody|Growth factor receptor bound protein 2-associated protein 1 antibody|Anti-GAB1 antibody (ab59362)
SCBT cat No: sc-6292|sc-271848|sc-9049|sc-133191|sc-25498|

 

Name

Gab 1 (phospho Tyr627) Polyclonal Antibody

Catalogue No.

STJ90278

Reactivity

Human, Mouse, Monkey

Specificity

Phospho-Gab 1 (Y627) Polyclonal Antibody detects endogenous levels of Gab 1 protein only when phosphorylated at Y627.

Immunogen

Synthesized phospho-peptide derived from Gab 1 (phospho Tyr627) at AA range 570-650

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

110/80 kDa

Formulation

Gab 1 (phospho Tyr627) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Gab 1 (phospho Tyr627) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

GRB2-associated-binding protein 1 antibody, GRB2-associated binder 1 antibody, Growth factor receptor bound protein 2-associated protein 1 antibody

Database links

Human UniProt/Swiss-Prot:Q13480;Mouse UniPort/Swiss-Prot: Q9QYY0;Human Entrez Gene: 2549;Mouse Entrez Gene: 14388;Rat Entrez Gene: Rn.1725

Protein names

GRB2-associated-binding protein 1 , GRB2-associated binder 1 , Growth factor receptor bound protein 2-associated protein 1

Protein function

Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).

Protein sequence and domain

Belongs to the GAB family. / Contains 1 PH domain.

Protein post-translational modifications

Phosphorylated in response to FGFR1 activation. Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains. Phosphorylated on tyrosine residues by HCK upon IL6 signaling.

Research area

All research areas>Signaling Intermediates>Gab
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize Gab 1 (phospho Tyr627) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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