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Rabbit Polyclonal Phospho-GAB1-Y627 antibody (AP0256)
Supplier: ABclonal Inc.
Recommended applications: WB,IF
WB 1:500 – 1:2000
IF 1:100 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit Polyclonal Phospho-GAB1-Y627 antibody.
Check alternative names for the antibodyExpand
Gab 1 antibody|GAB1 antibody|GAB1_HUMAN antibody|GRB 2 associated binder 1 antibody|GRB 2 associated binding protein 1 antibody|GRB2 associated binding protein 1 isoform a antibody|GRB2 associated binding protein 1 isoform b antibody|GRB2-associated binder 1 antibody|GRB2-associated-binding protein 1 antibody|Growth factor receptor bound protein 2-associated protein 1 antibody|Anti-GAB1 antibody (ab59362)
SCBT cat No: sc-6292|sc-271848|sc-9049|sc-133191|sc-25498|
Rabbit Polyclonal Phospho-GAB1-Y627 antibody
|Catalogue No.|| |
A phospho specific peptide corresponding to residues surrounding Y627 of human GAB1
|Recommended dilution|| |
WB 1:500 – 1:2000<br/>IF 1:100 – 1:200
|Molecular weight|| |
Phospho-GAB1-Y627 antibody was tube-contained.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
Human UniProt/Swiss-Prot:<a href="http://www.uniprot.org/uniprot/Q13480">Q13480</a>
|Protein function|| |
Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).
|Protein sequence and domain|| |
Belongs to the GAB family.; Contains 1 PH domain.
|Protein post-translational modifications|| |
Phosphorylated in response to FGFR1 activation. Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains. Phosphorylated on tyrosine residues by HCK upon IL6 signaling.
The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Signaling-Intermediates/">Signaling Intermediates</a>><a href="http://antibodyplus.com/product-tag/Gab/">Gab</a><br><a href="http://antibodyplus.com/product-tag/Signaling-Intermediates/"> (View all antibody categories related to Signaling Intermediates)</a>
AntibodyPlus can customize Phospho-GAB1-Y627 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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