Rabbit Polyclonal Phospho-GATA-2 (S401) antibody (STJ90518)

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Reactivity: Human, Monkey
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-GATA-2 (S401) antibody (STJ90518)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for GATA-2 (phospho Ser401) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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GATA2 antibody,|DCML antibody|Endothelial transcription factor GATA 2 antibody|GATA binding factor 3 antibody|GATA binding protein 2 antibody|GATA binding protein 3 antibody|HDR antibody|HDRS antibody|IMD21 antibody|MONOMAC antibody|NFE1B antibody|Trans acting T cell specific transcription factor GATA 3 antibody|Anti-GATA2 antibody – ChIP Grade (ab22849)
SCBT cat No: sc-267|sc-16044|sc-9008|sc-515178|sc-1235|

 

Name

GATA-2 (phospho Ser401) Polyclonal Antibody

Catalogue No.

STJ90518

Reactivity

Human, Monkey

Specificity

Phospho-GATA-2 (S401) Polyclonal Antibody detects endogenous levels of GATA-2 protein only when phosphorylated at S401.

Immunogen

Synthesized phospho-peptide derived from GATA-2 (phospho Ser401) at AA range 340-420

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

50 kDa

Formulation

GATA-2 (phospho Ser401) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

GATA-2 (phospho Ser401) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Endothelial transcription factor GATA-2 antibody, GATA-binding protein 2 antibody

Database links

Human UniProt/Swiss-Prot:P23769;Mouse UniPort/Swiss-Prot: O09100;Rat UniProt/Swiss-Port: Q924Y4;Human Entrez Gene: 2624;Mouse Entrez Gene: 14461;Rat Entrez Gene: Rn.34322

Protein names

Endothelial transcription factor GATA-2 , GATA-binding protein 2

Protein function

Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5′-AGATAG-3′.

Protein tissue specificity

Endothelial cells.

Involvement in disease

Immunodeficiency 21 (IMD21) [MIM:614172]: An immunodeficiency disease characterized by profoundly decreased or absent monocytes, B-lymphocytes, natural killer lymphocytes, and circulating and tissue dendritic cells, with little or no effect on T-cell numbers. Clinical features of DCML include susceptibility to disseminated non-tuberculous mycobacterial infections, papillomavirus infections, opportunistic fungal infections, and pulmonary alveolar proteinosis. Bone marrow hypocellularity and dysplasia of myeloid, erythroid, and megakaryocytic lineages are present in most patients, as are karyotypic abnormalities, including monosomy 7 and trisomy 8. This syndrome links susceptibility to mycobacterial, viral, and fungal infections with malignancy and can be transmitted in an autosomal dominant pattern. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Lymphedema, primary, with myelodysplasia (LMPM) [MIM:614038]: A chronic disabling condition characterized by swelling of the extremities due to altered lymphatic flow, associated with myelodysplasia. Patients with lymphedema suffer from recurrent local infections, and physical impairment. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Myelodysplastic syndrome (MDS) [MIM:614286]: A heterogeneous group of closely related clonal hematopoietic disorders. All are characterized by a hypercellular or hypocellular bone marrow with impaired morphology and maturation, dysplasia of the myeloid, megakaryocytic and/or erythroid lineages, and peripheral blood cytopenias resulting from ineffective blood cell production. Included diseases are: refractory anemia (RA), refractory anemia with ringed sideroblasts (RARS), refractory anemia with excess blasts (RAEB), refractory cytopenia with multilineage dysplasia and ringed sideroblasts (RCMD-RS); chronic myelomonocytic leukemia (CMML) is a myelodysplastic/myeloproliferative disease. MDS is considered a premalignant condition in a subgroup of patients that often progresses to acute myeloid leukemia (AML). . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Contains 2 GATA-type zinc fingers.

Protein cellular localization

Nucleus

Research area

All research areas>Transcription Regulators>GATA
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize GATA-2 (phospho Ser401) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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