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Rabbit Polyclonal Phospho-GATA-2 (S401) antibody (STJ90518)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:5000;
Recommended protocols: check protocols
Click or hover above images to see image description for GATA-2 (phospho Ser401) Polyclonal Antibody.
Check alternative names for the antibodyExpand
GATA2 antibody,|DCML antibody|Endothelial transcription factor GATA 2 antibody|GATA binding factor 3 antibody|GATA binding protein 2 antibody|GATA binding protein 3 antibody|HDR antibody|HDRS antibody|IMD21 antibody|MONOMAC antibody|NFE1B antibody|Trans acting T cell specific transcription factor GATA 3 antibody|Anti-GATA2 antibody – ChIP Grade (ab22849)
SCBT cat No: sc-267|sc-16044|sc-9008|sc-515178|sc-1235|
GATA-2 (phospho Ser401) Polyclonal Antibody
|Catalogue No.|| |
Phospho-GATA-2 (S401) Polyclonal Antibody detects endogenous levels of GATA-2 protein only when phosphorylated at S401.
Synthesized phospho-peptide derived from GATA-2 (phospho Ser401) at AA range 340-420
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:5000;
|Molecular weight|| |
GATA-2 (phospho Ser401) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
GATA-2 (phospho Ser401) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Endothelial transcription factor GATA-2 antibody, GATA-binding protein 2 antibody
|Protein names|| |
Endothelial transcription factor GATA-2 , GATA-binding protein 2
|Protein function|| |
Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5′-AGATAG-3′.
|Protein tissue specificity|| |
|Involvement in disease|| |
Immunodeficiency 21 (IMD21) [MIM:614172]: An immunodeficiency disease characterized by profoundly decreased or absent monocytes, B-lymphocytes, natural killer lymphocytes, and circulating and tissue dendritic cells, with little or no effect on T-cell numbers. Clinical features of DCML include susceptibility to disseminated non-tuberculous mycobacterial infections, papillomavirus infections, opportunistic fungal infections, and pulmonary alveolar proteinosis. Bone marrow hypocellularity and dysplasia of myeloid, erythroid, and megakaryocytic lineages are present in most patients, as are karyotypic abnormalities, including monosomy 7 and trisomy 8. This syndrome links susceptibility to mycobacterial, viral, and fungal infections with malignancy and can be transmitted in an autosomal dominant pattern. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Lymphedema, primary, with myelodysplasia (LMPM) [MIM:614038]: A chronic disabling condition characterized by swelling of the extremities due to altered lymphatic flow, associated with myelodysplasia. Patients with lymphedema suffer from recurrent local infections, and physical impairment. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Myelodysplastic syndrome (MDS) [MIM:614286]: A heterogeneous group of closely related clonal hematopoietic disorders. All are characterized by a hypercellular or hypocellular bone marrow with impaired morphology and maturation, dysplasia of the myeloid, megakaryocytic and/or erythroid lineages, and peripheral blood cytopenias resulting from ineffective blood cell production. Included diseases are: refractory anemia (RA), refractory anemia with ringed sideroblasts (RARS), refractory anemia with excess blasts (RAEB), refractory cytopenia with multilineage dysplasia and ringed sideroblasts (RCMD-RS); chronic myelomonocytic leukemia (CMML) is a myelodysplastic/myeloproliferative disease. MDS is considered a premalignant condition in a subgroup of patients that often progresses to acute myeloid leukemia (AML). . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Contains 2 GATA-type zinc fingers.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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