Rabbit Polyclonal Phospho-GluR-1 (S863) antibody (STJ91008)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-GluR-1 (S863) antibody (STJ91008)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for GluR-1 (phospho Ser863) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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GRIA1 antibody, GLUH1 antibody, GLUR1 antibody,|GLUR 1 antibody| GLUR A antibody|AMPA 1 antibody|AMPA selective glutamate receptor 1 antibody|AMPA-selective glutamate receptor 1 antibody|GluA1 antibody|GLUH1 antibody|GluR K1 antibody|GluR-1 antibody|GluR-A antibody|GluR-K1 antibody|GLUR1 antibody|GLURA antibody|GluRK1 antibody|Glutamate receptor 1 antibody|Glutamate receptor ionotropic AMPA 1 antibody|Glutamate receptor ionotropic antibody|Glutamate receptor, ionotropic, AMPA 1 antibody|Gria1 antibody|GRIA1_HUMAN antibody|HBGR1 antibody|MGC133252 antibody|OTTHUMP00000160643 antibody|OTTHUMP00000165781 antibody|OTTHUMP00000224241 antibody|OTTHUMP00000224242 antibody|OTTHUMP00000224243 antibody|Anti-Glutamate Receptor 1 (AMPA subtype) antibody (ab31232)
SCBT cat No: sc-7609|sc-13152|sc-55509|sc-28799|sc-33612|sc-7610|sc-7611|sc-517202|

 

Name

GluR-1 (phospho Ser863) Polyclonal Antibody

Catalogue No.

STJ91008

Reactivity

Human, Mouse, Rat

Specificity

Phospho-GluR-1 (S863) Polyclonal Antibody detects endogenous levels of GluR-1 protein only when phosphorylated at S863.

Immunogen

Synthesized phospho-peptide derived from GluR-1 (phospho Ser863) at AA range 800-880

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

102 kDa

Formulation

GluR-1 (phospho Ser863) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

GluR-1 (phospho Ser863) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Glutamate receptor 1 antibody, GluR-1 antibody, AMPA-selective glutamate receptor 1 antibody, GluR-A antibody, GluR-K1 antibody, Glutamate receptor ionotropic, AMPA 1 antibody, GluA1 antibody

Database links

Human UniProt/Swiss-Prot:P42261;Mouse UniPort/Swiss-Prot: P23818;Rat UniProt/Swiss-Port: P19490;Human Entrez Gene: 2890;Mouse Entrez Gene: 14799;Rat Entrez Gene: Rn.29971

Protein names

Glutamate receptor 1 , GluR-1 , AMPA-selective glutamate receptor 1 , GluR-A , GluR-K1 , Glutamate receptor ionotropic, AMPA 1 , GluA1

Protein function

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Protein tissue specificity

Widely expressed in brain.

Protein sequence and domain

The M4 transmembrane segment mediates tetramerization and is required for cell surface expression. / Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA1 subfamily. [View classification]

Protein post-translational modifications

Palmitoylated. Depalmitoylated upon glutamate stimulation. Cys-603 palmitoylation leads to Golgi retention and decreased cell surface expression. In contrast, Cys-829 palmitoylation does not affect cell surface expression but regulates stimulation-dependent endocytosis (By similarity).

Protein cellular localization

Cell membrane / Multi-pass membrane protein / Endoplasmic reticulum membrane / Cell junction > synapse > postsynaptic cell membrane / Multi-pass membrane protein / Cell junction > synapse > postsynaptic cell membrane > postsynaptic density / Cell projection > dendrite / Cell projection > dendritic spine

Research area

All research areas>Channel Proteins>GluR
(View all antibody categories related to Channel Proteins)

Note

AntibodyPlus can customize GluR-1 (phospho Ser863) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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