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Rabbit Polyclonal Phospho-GluR-1 (S863) antibody (STJ91008)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;
Recommended protocols: check protocols
Click or hover above images to see image description for GluR-1 (phospho Ser863) Polyclonal Antibody.
Check alternative names for the antibodyExpand
GRIA1 antibody, GLUH1 antibody, GLUR1 antibody,|GLUR 1 antibody| GLUR A antibody|AMPA 1 antibody|AMPA selective glutamate receptor 1 antibody|AMPA-selective glutamate receptor 1 antibody|GluA1 antibody|GLUH1 antibody|GluR K1 antibody|GluR-1 antibody|GluR-A antibody|GluR-K1 antibody|GLUR1 antibody|GLURA antibody|GluRK1 antibody|Glutamate receptor 1 antibody|Glutamate receptor ionotropic AMPA 1 antibody|Glutamate receptor ionotropic antibody|Glutamate receptor, ionotropic, AMPA 1 antibody|Gria1 antibody|GRIA1_HUMAN antibody|HBGR1 antibody|MGC133252 antibody|OTTHUMP00000160643 antibody|OTTHUMP00000165781 antibody|OTTHUMP00000224241 antibody|OTTHUMP00000224242 antibody|OTTHUMP00000224243 antibody|Anti-Glutamate Receptor 1 (AMPA subtype) antibody (ab31232)
SCBT cat No: sc-7609|sc-13152|sc-55509|sc-28799|sc-33612|sc-7610|sc-7611|sc-517202|
GluR-1 (phospho Ser863) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-GluR-1 (S863) Polyclonal Antibody detects endogenous levels of GluR-1 protein only when phosphorylated at S863.
Synthesized phospho-peptide derived from GluR-1 (phospho Ser863) at AA range 800-880
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;
|Molecular weight|| |
GluR-1 (phospho Ser863) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
GluR-1 (phospho Ser863) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Glutamate receptor 1 antibody, GluR-1 antibody, AMPA-selective glutamate receptor 1 antibody, GluR-A antibody, GluR-K1 antibody, Glutamate receptor ionotropic, AMPA 1 antibody, GluA1 antibody
|Protein names|| |
Glutamate receptor 1 , GluR-1 , AMPA-selective glutamate receptor 1 , GluR-A , GluR-K1 , Glutamate receptor ionotropic, AMPA 1 , GluA1
|Protein function|| |
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
|Protein tissue specificity|| |
Widely expressed in brain.
|Protein sequence and domain|| |
The M4 transmembrane segment mediates tetramerization and is required for cell surface expression. / Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA1 subfamily. [View classification]
|Protein post-translational modifications|| |
Palmitoylated. Depalmitoylated upon glutamate stimulation. Cys-603 palmitoylation leads to Golgi retention and decreased cell surface expression. In contrast, Cys-829 palmitoylation does not affect cell surface expression but regulates stimulation-dependent endocytosis (By similarity).
|Protein cellular localization|| |
Cell membrane / Multi-pass membrane protein / Endoplasmic reticulum membrane / Cell junction > synapse > postsynaptic cell membrane / Multi-pass membrane protein / Cell junction > synapse > postsynaptic cell membrane > postsynaptic density / Cell projection > dendrite / Cell projection > dendritic spine
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St John’s Laboratory Ltd.
|Product type|| |
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