Rabbit Polyclonal Phospho-GluR4 (S862) antibody (STJ90900)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-GluR4 (S862) antibody (STJ90900)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for GluR4 (phospho Ser862) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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GRIA4 antibody, GLUR4 antibody,|AMPA 4 antibody|AMPA selective glutamate receptor 4 antibody|AMPA-selective glutamate receptor 4 antibody|AMPA4 antibody|GluA 4 antibody|GluA4 antibody|GluR 4 antibody|GluR D antibody|GluR-4 antibody|GluR-D antibody|GluR4 antibody|GLUR4C antibody|GLURD antibody|Glutamate receptor 4 antibody|Glutamate receptor ionotrophic AMPA 4 antibody|Glutamate receptor ionotropic antibody|GRIA 4 antibody|Gria4 antibody|GRIA4_HUMAN antibody|Anti-Ionotropic Glutamate receptor 4 antibody (ab77407)
SCBT cat No: sc-7614|sc-271894|sc-31394|

 

Name

GluR4 (phospho Ser862) Polyclonal Antibody

Catalogue No.

STJ90900

Reactivity

Human, Mouse, Rat

Specificity

Phospho-GluR4 (S862) Polyclonal Antibody detects endogenous levels of GluR4 protein only when phosphorylated at S862.

Immunogen

Synthesized phospho-peptide derived from GluR4 (phospho Ser862) at AA range 800-880

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

100 kDa

Formulation

GluR4 (phospho Ser862) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

GluR4 (phospho Ser862) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Glutamate receptor 4 antibody, GluR-4 antibody, GluR4 antibody, AMPA-selective glutamate receptor 4 antibody, GluR-D antibody, Glutamate receptor ionotropic, AMPA 4 antibody, GluA4 antibody

Database links

Human UniProt/Swiss-Prot:P48058;Mouse UniPort/Swiss-Prot: Q9Z2W8;Rat UniProt/Swiss-Port: P19493;Human Entrez Gene: 2893;Mouse Entrez Gene: 14802;Rat Entrez Gene: Rn.10938

Protein names

Glutamate receptor 4 , GluR-4 , GluR4 , AMPA-selective glutamate receptor 4 , GluR-D , Glutamate receptor ionotropic, AMPA 4 , GluA4

Protein function

Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Protein sequence and domain

The M4 transmembrane segment mediates tetramerization and is required for cell surface expression. / Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA4 subfamily. [View classification]

Protein post-translational modifications

Palmitoylated. Depalmitoylated upon glutamate stimulation. Cys-611 palmitoylation leads to Golgi retention and decreased cell surface expression. In contrast, Cys-837 palmitoylation does not affect cell surface expression but regulates stimulation-dependent endocytosis (By similarity). / Phosphorylated at Ser-862 by PRKCG; phosphorylation increases plasma membrane-associated GRI4 expression.

Protein cellular localization

Cell membrane; Multi-pass membrane protein / Cell junction > synapse > postsynaptic cell membrane; Multi-pass membrane protein / Cell projection > dendrite

Research area

All research areas>Channel Proteins>GluR
(View all antibody categories related to Channel Proteins)

Note

AntibodyPlus can customize GluR4 (phospho Ser862) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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