Rabbit Polyclonal Phospho-GRIA1-S849 antibody (AP0242)


Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-GRIA1-S849 antibody (AP0242)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody


GLUH1 antibody; GLUR1 antibody; GLURA antibody; GluA1 antibody; HBGR1 antibody;
GLUR 1 antibody| GLUR A antibody|AMPA 1 antibody|AMPA selective glutamate receptor 1 antibody|AMPA-selective glutamate receptor 1 antibody|GluA1 antibody|GLUH1 antibody|GluR K1 antibody|GluR-1 antibody|GluR-A antibody|GluR-K1 antibody|GLUR1 antibody|GLURA antibody|GluRK1 antibody|Glutamate receptor 1 antibody|Glutamate receptor ionotropic AMPA 1 antibody|Glutamate receptor ionotropic antibody|Glutamate receptor, ionotropic, AMPA 1 antibody|Gria1 antibody|GRIA1_HUMAN antibody|HBGR1 antibody|MGC133252 antibody|OTTHUMP00000160643 antibody|OTTHUMP00000165781 antibody|OTTHUMP00000224241 antibody|OTTHUMP00000224242 antibody|OTTHUMP00000224243 antibody|Anti-Glutamate Receptor 1 (AMPA subtype) antibody (ab31232)

SCBT cat No: sc-7609|sc-13152|sc-55509|sc-28799|sc-33612|sc-7610|sc-7611|sc-517202|


Rabbit Polyclonal Phospho-GRIA1-S849 antibody

Catalogue No.



Human, Mouse, Rat


A phospho specific peptide corresponding to residues surrounding S849 of human GRIA1











Molecular weight



Phospho-GRIA1-S849 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


Affinity purification


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

GLUH1 antibody; GLUR1 antibody; GLURA antibody; GluA1 antibody; HBGR1 antibody;

Protein names


Protein function

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Protein tissue specificity

Widely expressed in brain.

Protein sequence and domain

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA1 subfamily. The M4 transmembrane segment mediates tetramerization and is required for cell surface expression.

Protein post-translational modifications

Palmitoylated. Depalmitoylated upon glutamate stimulation. Cys-603 palmitoylation leads to Golgi retention and decreased cell surface expression. In contrast, Cys-829 palmitoylation does not affect cell surface expression but regulates stimulation-dependent endocytosis (By similarity).

Protein cellular localization

Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Cell projection, dendrite . Cell projection, dendritic spine . Note=Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression.


Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research area

<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Channel-Proteins/">Channel Proteins</a>><a href="http://antibodyplus.com/product-tag/GluR/">GluR</a><br><a href="http://antibodyplus.com/product-tag/Channel-Proteins/"&gt; (View all antibody categories related to Channel Proteins)</a>


AntibodyPlus can customize Phospho-GRIA1-S849 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


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