Rabbit Polyclonal Phospho-GRK 2 (S685) antibody (STJ90616)


Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-GRK 2 (S685) antibody (STJ90616)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for GRK 2 (phospho Ser685) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody


ADRBK1 antibody, BARK antibody, BARK1 antibody, GRK2 antibody,|ADRBK1 antibody|Adrenergic beta receptor kinase 1 antibody|ARBK1_HUMAN antibody|BARK antibody|BARK1 antibody|Beta adrenergic receptor kinase 1 antibody|Beta ARK 1 antibody|Beta ARK1 antibody|Beta-adrenergic receptor kinase 1 antibody|Beta-ARK-1 antibody|FLJ16718 antibody|G protein coupled receptor kinase 2 antibody|G-protein coupled receptor kinase 2 antibody|GRK2 antibody|Anti-GRK2 antibody – C-terminal (ab137666)
SCBT cat No: sc-562|sc-18409|sc-13143|sc-166283|sc-166284|sc-271359|sc-8329|



GRK 2 (phospho Ser685) Polyclonal Antibody

Catalogue No.



Human, Mouse, Rat


Phospho-GRK 2 (S685) Polyclonal Antibody detects endogenous levels of GRK 2 protein only when phosphorylated at S685.


Synthesized phospho-peptide derived from GRK 2 (phospho Ser685) at AA range 620-700





Recommended dilution

WB 1:500-1:2000; ELISA 1:5000;







Molecular weight

80 kDa


GRK 2 (phospho Ser685) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.


1 mg/ml


GRK 2 (phospho Ser685) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.


-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Beta-adrenergic receptor kinase 1 antibody, Beta-ARK-1 antibody, G-protein coupled receptor kinase 2 antibody

Database links

Human UniProt/Swiss-Prot:P25098;Mouse UniPort/Swiss-Prot: Q99MK8;Rat UniProt/Swiss-Port: P26817;Human Entrez Gene: 156;Mouse Entrez Gene: 110355;Rat Entrez Gene: Rn.13010

Protein names

Beta-adrenergic receptor kinase 1 , Beta-ARK-1 , G-protein coupled receptor kinase 2

Protein function

Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. / ATP + [beta-adrenergic receptor] = ADP + [beta-adrenergic receptor] phosphate. / In contrast to other AGC family kinases, the catalytic activity is solely regulated by the binding of substrates and ligands, not by phosphorylation of the kinase domain.

Protein tissue specificity

Expressed in peripheral blood leukocytes.

Protein sequence and domain

The PH domain binds anionic phospholipids and helps recruiting ADRBK1 from the cytoplasm to plasma membrane close to activated receptors. It mediates binding to G protein beta and gamma subunits, competing with G-apha subunits and other G-betagamma effectors. / Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. / Contains 1 AGC-kinase C-terminal domain. / Contains 1 PH domain. / Contains 1 protein kinase domain. / Contains 1 RGS domain.

Protein cellular localization

Cytoplasm / Cell membrane

Research area

All research areas>Kinases and Phosphatases>GRK
(View all antibody categories related to Kinases and Phosphatases)


AntibodyPlus can customize GRK 2 (phospho Ser685) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.


St John’s Laboratory Ltd.

Product type

Primary antibody


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