No products in the cart.
Rabbit Polyclonal Phospho-HDAC2 (S394) antibody (STJ90442)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:20000;
Recommended protocols: check protocols
Click or hover above images to see image description for HDAC2 (phospho Ser394) Polyclonal Antibody.
Check alternative names for the antibodyExpand
HDAC2 antibody,|D10Wsu179e antibody|HD 2 antibody|HD2 antibody|HDAC 2 antibody|Hdac2 antibody|HDAC2_HUMAN antibody|Histone deacetylase 2 (HD2) antibody|Histone deacetylase 2 antibody|OTTHUMP00000017046 antibody|OTTHUMP00000227077 antibody|OTTHUMP00000227078 antibody|RPD3 antibody|transcriptional regulator homolog RPD3 antibody|YAF1 antibody|YY1 associated factor 1 antibody|YY1 transcription factor binding protein antibody|Yy1bp antibody|Anti-HDAC2 antibody [Y461] (ab32117)
SCBT cat No: sc-81599|sc-55541|sc-6296|sc-9959|sc-55542|sc-7899|sc-56685|sc-130319|
HDAC2 (phospho Ser394) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat, Monkey
Phospho-HDAC2 (S394) Polyclonal Antibody detects endogenous levels of HDAC2 protein only when phosphorylated at S394.
Synthesized phospho-peptide derived from HDAC2 (phospho Ser394) at AA range 330-410
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:20000;
|Molecular weight|| |
HDAC2 (phospho Ser394) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
HDAC2 (phospho Ser394) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Histone deacetylase 2 antibody, HD2 antibody,
|Protein names|| |
Histone deacetylase 2 , HD2 ,
|Protein function|| |
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. May be involved in the transcriptional repression of circadian target genes, such as PER1, mediated by CRY1 through histone deacetylation. Involved in MTA1-mediated transcriptional corepression of TFF1 and CDKN1A. / Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.
|Protein tissue specificity|| |
Widely expressed; lower levels in brain and lung.
|Protein sequence and domain|| |
Belongs to the histone deacetylase family. HD type 1 subfamily.
|Protein post-translational modifications|| |
S-nitrosylated by GAPDH. In neurons, S-Nitrosylation at Cys-262 and Cys-274 does not affect the enzyme activity but abolishes chromatin-binding, leading to increases acetylation of histones and activate genes that are associated with neuronal development. In embryonic cortical neurons, S-Nitrosylation regulates dendritic growth and branching. S-Nitrosylation interferes with its interaction with MTA1 (By similarity).
|Protein cellular localization|| |
Nucleus / Cytoplasm
AntibodyPlus can customize HDAC2 (phospho Ser394) Antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: