Rabbit Polyclonal Phospho-HDAC7 (S155) antibody (STJ90655)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-HDAC7 (S155) antibody (STJ90655)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:40000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for HDAC7 (phospho Ser155) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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HDAC7 antibody, HDAC7A antibody,|DKFZP586J0917 antibody|FLJ99588 antibody|HD 7a antibody|HD7 antibody|HD7a antibody|HDAC 7 antibody|HDAC 7A antibody|Hdac7 antibody|HDAC7_HUMAN antibody|HDAC7A antibody|Histone deacetylase 7 antibody|Histone deacetylase 7A antibody|OTTHUMP00000202813 antibody|OTTHUMP00000202814 antibody|Anti-HDAC7 antibody (ab12174)
SCBT cat No: sc-11421|sc-133106|sc-133225|sc-5250|sc-11419|

 

Name

HDAC7 (phospho Ser155) Polyclonal Antibody

Catalogue No.

STJ90655

Reactivity

Human, Mouse, Rat

Specificity

Phospho-HDAC7 (S155) Polyclonal Antibody detects endogenous levels of HDAC7 protein only when phosphorylated at S155.

Immunogen

Synthesized phospho-peptide derived from HDAC7 (phospho Ser155) at AA range 90-170

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:40000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

103 kDa

Formulation

HDAC7 (phospho Ser155) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

HDAC7 (phospho Ser155) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Histone deacetylase 7 antibody, HD7 antibody, Histone deacetylase 7A antibody, HD7a antibody

Database links

Human UniProt/Swiss-Prot:Q8WUI4;Mouse UniPort/Swiss-Prot: Q8C2B3;Rat UniProt/Swiss-Port: A0A0G2K6B1;Human Entrez Gene: 51564;Mouse Entrez Gene: 56233;Rat Entrez Gene: Rn.203327

Protein names

Histone deacetylase 7 , HD7 , Histone deacetylase 7A , HD7a

Protein function

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 . / Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.

Protein sequence and domain

The nuclear export sequence mediates the shuttling between the nucleus and the cytoplasm. / Belongs to the histone deacetylase family. HD type 2 subfamily.

Protein post-translational modifications

May be phosphorylated by CaMK1. Phosphorylated by the PKC kinases PKN1 and PKN2, impairing nuclear import. Phosphorylation at Ser-155 by MARK2, MARK3 and PRKD1 promotes interaction with 14-3-3 proteins and export from the nucleus. Phosphorylation at Ser-155 is a prerequisite for phosphorylation at Ser-181.

Protein cellular localization

Nucleus / Cytoplasm

Research area

All research areas>Transcription Regulators>HDAC
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize HDAC7 (phospho Ser155) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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