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Rabbit Polyclonal Phospho-Histone H1 (T17) antibody (STJ91085)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, IF, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000;
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
HIST1H1B antibody, H1F5 antibody,|dJ221C16.2 antibody|dJ221C16.5 antibody|DmeH1 antibody|H1 0 histone antibody|H1 antibody|H1 histone family member 0 antibody|H1 histone family member 1 antibody|H1 histone family member 3 antibody|H1 histone family member 5 antibody|H1 histone family member N testis specific antibody|H1 histone family member O oocyte specific antibody|H1 histone family member X antibody|H1(0) antibody|H1.1 antibody|H1.2 antibody|H1.3 antibody|H1.4 antibody|H1.5 antibody|H10 antibody|H1A antibody|H1f0 antibody|H1F0 protein antibody|H1F1 antibody|H1F2 antibody|H1F3 antibody|H1F4 antibody|H1F5 antibody|H1FNT antibody|H1FOO antibody|H1FOO protein antibody|H1FOO_HUMAN antibody|H1FT antibody|H1FV antibody|H1FX antibody|H1oo antibody|H1t antibody|H1T2 antibody|H1X antibody|HANP1 antibody|His1 antibody|HisC antibody|HIST1 antibody|HIST1H1A antibody|HIST1H1B antibody|HIST1H1C antibody|HIST1H1D antibody|HIST1H1E antibody|HIST1H1T antibody|Histone 1 H1a antibody|Histone 1 H1b antibody|Histone 1 H1c antibody|Histone 1 H1d antibody|Histone 1 H1e antibody|Histone 1 H1t antibody|Histone antibody|Histone H1′ antibody|Histone H1.0 antibody|Histone H1.1 antibody|Histone H1.2 antibody|Histone H1.3 antibody|Histone H1.4 antibody|Histone H1.5 antibody|Histone H1oo antibody|Histone H1x antibody|MGC116819 antibody|MGC126630 antibody|MGC126632 antibody|MGC126642 antibody|MGC138176 antibody|MGC138345 antibody|MGC15959 antibody|MGC3992 antibody|MGC50807 antibody|MGC5241 antibody|MGC8350 antibody|Oocyte specific histone H1 antibody|Oocyte specific linker histone H1 antibody|Oocyte-specific histone H1 antibody|Oocyte-specific linker histone H1 antibody|osH1 antibody|Testicular H1 histone antibody|Anti-Histone H1 antibody (ab71594)
SCBT cat No: sc-514856|
Histone H1 (phospho Thr17) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Monkey
Phospho-Histone H1 (T17) Polyclonal Antibody detects endogenous levels of Histone H1 protein only when phosphorylated at T17.
Synthesized phospho-peptide derived from Histone H1 (phospho Thr17) at AA range 1-80
WB, IHC, IF, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000;
|Molecular weight|| |
Histone H1 (phospho Thr17) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Histone H1 (phospho Thr17) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Histone H1.5 antibody, Histone H1a antibody, Histone H1b antibody, Histone H1s-3 antibody
|Protein names|| |
Histone H1.5 , Histone H1a , Histone H1b , Histone H1s-3
|Protein function|| |
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
|Protein tissue specificity|| |
Ubiquitous. Expressed in the majority of the cell lines tested and in testis.
|Protein sequence and domain|| |
The C-terminal domain is required for high-affinity binding to chromatin. / Belongs to the histone H1/H5 family. / Contains 1 H15 (linker histone H1/H5 globular) domain.
|Protein post-translational modifications|| |
H1 histones are progressively phosphorylated during the cell cycle, becoming maximally phosphorylated during late G2 phase and M phase, and being dephosphorylated sharply thereafter (By similarity). Phosphorylated at Thr-11 by GSK3B during mitosis in prometaphase and dephosphorylated in telophase. / Citrullination at Arg-57 (H1R54ci) by PADI4 takes place within the DNA-binding site of H1 and results in its displacement from chromatin and global chromatin decondensation, thereby promoting pluripotency and stem cell maintenance.
|Protein cellular localization|| |
Nucleus / Chromosome
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St John’s Laboratory Ltd.
|Product type|| |
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