Rabbit Polyclonal Phospho-HP1gamma (S93) antibody (STJ90610)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-HP1gamma (S93) antibody (STJ90610)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for HP1gamma (phospho Ser93) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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CBX3 antibody,|CBX 3 antibody|CBX3 antibody|CBX3_HUMAN antibody|Chromobox homolog 3 (HP1 gamma homolog, Drosophila) antibody|Chromobox homolog 3 antibody|Chromobox protein homolog 3 antibody|GAMMA antibody|HECH antibody|Heterochromatin like protein 1 antibody|Heterochromatin protein 1 homolog gamma antibody|Heterochromatin protein HP1 gamma antibody|HP1 gamma antibody|HP1 gamma homolog antibody|HP1Hs gamma antibody|Modifier 2 protein antibody|Phospho anti-HP1 gamma (S93) antibody (ab45270)
SCBT cat No: sc-10214|sc-365085|sc-398562|sc-10213|

 

Name

HP1gamma (phospho Ser93) Polyclonal Antibody

Catalogue No.

STJ90610

Reactivity

Human, Mouse, Rat

Specificity

Phospho-HP1gamma (S93) Polyclonal Antibody detects endogenous levels of HP1gamma protein only when phosphorylated at S93.

Immunogen

Synthesized phospho-peptide derived from HP1gamma (phospho Ser93) at AA range 30-110

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

24 kDa

Formulation

HP1gamma (phospho Ser93) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

HP1gamma (phospho Ser93) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Chromobox protein homolog 3 antibody, HECH antibody, Heterochromatin protein 1 homolog gamma antibody, HP1 gamma antibody, Modifier 2 protein antibody

Database links

Human UniProt/Swiss-Prot:Q13185;Rat UniProt/Swiss-Port: Q5RJK5;Human Entrez Gene: 11335;Mouse Entrez Gene: 12417;

Protein names

Chromobox protein homolog 3 , HECH , Heterochromatin protein 1 homolog gamma , HP1 gamma , Modifier 2 protein

Protein function

Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at ‘Lys-9’, leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 ‘Lys-9’ trimethylation, mediates the recruitment of the mehtyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.

Protein sequence and domain

Contains 2 chromo domains.

Protein post-translational modifications

Phosphorylated by PIM1. Phosphorylated during interphase and possibly hyper-phosphorylated during mitosis.

Protein cellular localization

Nucleus

Research area

All research areas>Transcription Regulators>HP1
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize HP1gamma (phospho Ser93) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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