Rabbit Polyclonal Phospho-HSL (S552) antibody (STJ90796)

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Reactivity: Human, Mouse, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-HSL (S552) antibody (STJ90796)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for HSL (phospho Ser552) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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LIPE antibody,|Hormone sensitive lipase antibody|Hormone sensitive lipase testicular isoform antibody|Hormone-sensitive lipase antibody|HSL antibody|LHS antibody|Lipase hormone sensitive antibody|LIPE antibody|LIPS_HUMAN antibody|Anti-Hormone sensitive lipase antibody (ab45422)
SCBT cat No: sc-74489|sc-25843|sc-27954|

 

Name

HSL (phospho Ser552) Polyclonal Antibody

Catalogue No.

STJ90796

Reactivity

Human, Mouse, Rat

Specificity

Phospho-HSL (S552) Polyclonal Antibody detects endogenous levels of HSL protein only when phosphorylated at S552.

Immunogen

Synthesized phospho-peptide derived from HSL (phospho Ser552) at AA range 490-570

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

117 kDa

Formulation

HSL (phospho Ser552) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

HSL (phospho Ser552) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Hormone-sensitive lipase antibody, HSL antibody,

Database links

Human UniProt/Swiss-Prot:Q05469;Mouse UniPort/Swiss-Prot: P54310;Rat UniProt/Swiss-Port: P15304;Human Entrez Gene: 3991;Mouse Entrez Gene: 16890;Rat Entrez Gene: Rn.10566

Protein names

Hormone-sensitive lipase , HSL ,

Protein function

In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. / Diacylglycerol + H2O = monoacylglycerol + a carboxylate. / Triacylglycerol + H2O = diacylglycerol + a carboxylate. / Monoacylglycerol + H2O = glycerol + a carboxylate. / Rapidly activated by cAMP-dependent phosphorylation under the influence of catecholamines. Dephosphorylation and inactivation are controlled by insulin. /

Involvement in disease

Lipodystrophy, familial partial, 6 (FPLD6) [MIM:615980]: A form of lipodystrophy characterized by abnormal subcutaneous fat distribution. Affected individuals have increased visceral fat, impaired lipolysis, dyslipidemia, hepatic steatosis, systemic insulin resistance, and diabetes. Some patients manifest muscular dystrophy. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the ‘GDXG’ lipolytic enzyme family.

Protein post-translational modifications

Phosphorylation by AMPK may block translocation to lipid droplets.

Protein cellular localization

Cell membrane / Membrane > caveola / Cytoplasm > cytosol

Research area

All research areas>Signaling Intermediates>HSL
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize HSL (phospho Ser552) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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