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Rabbit Polyclonal Phospho-HSL (S552) antibody (STJ90796)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
Recommended protocols: check protocols
Click or hover above images to see image description for HSL (phospho Ser552) Polyclonal Antibody.
Check alternative names for the antibodyExpand
LIPE antibody,|Hormone sensitive lipase antibody|Hormone sensitive lipase testicular isoform antibody|Hormone-sensitive lipase antibody|HSL antibody|LHS antibody|Lipase hormone sensitive antibody|LIPE antibody|LIPS_HUMAN antibody|Anti-Hormone sensitive lipase antibody (ab45422)
SCBT cat No: sc-74489|sc-25843|sc-27954|
HSL (phospho Ser552) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-HSL (S552) Polyclonal Antibody detects endogenous levels of HSL protein only when phosphorylated at S552.
Synthesized phospho-peptide derived from HSL (phospho Ser552) at AA range 490-570
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
|Molecular weight|| |
HSL (phospho Ser552) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
HSL (phospho Ser552) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Hormone-sensitive lipase antibody, HSL antibody,
|Protein names|| |
Hormone-sensitive lipase , HSL ,
|Protein function|| |
In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. / Diacylglycerol + H2O = monoacylglycerol + a carboxylate. / Triacylglycerol + H2O = diacylglycerol + a carboxylate. / Monoacylglycerol + H2O = glycerol + a carboxylate. / Rapidly activated by cAMP-dependent phosphorylation under the influence of catecholamines. Dephosphorylation and inactivation are controlled by insulin. /
|Involvement in disease|| |
Lipodystrophy, familial partial, 6 (FPLD6) [MIM:615980]: A form of lipodystrophy characterized by abnormal subcutaneous fat distribution. Affected individuals have increased visceral fat, impaired lipolysis, dyslipidemia, hepatic steatosis, systemic insulin resistance, and diabetes. Some patients manifest muscular dystrophy. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the ‘GDXG’ lipolytic enzyme family.
|Protein post-translational modifications|| |
Phosphorylation by AMPK may block translocation to lipid droplets.
|Protein cellular localization|| |
Cell membrane / Membrane > caveola / Cytoplasm > cytosol
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St John’s Laboratory Ltd.
|Product type|| |
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