Rabbit Polyclonal Phospho-HSPB1-S82 antibody (AP0237)


Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-HSPB1-S82 antibody (AP0237)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody


CMT2F antibody; HMN2B antibody; HSP27 antibody; HSP28 antibody; Hsp25 antibody; SRP27 antibody; HS.76067 antibody;
Heat shock 27kDa protein antibody|28 kDa heat shock protein antibody|CMT2F antibody|DKFZp586P1322 antibody|epididymis secretory protein Li 102 antibody|Estrogen regulated 24 kDa protein antibody|Estrogen-regulated 24 kDa protein antibody|Heat shock 25kDa protein 1 antibody|Heat shock 27 kDa protein antibody|Heat shock 27kD protein 1 antibody|Heat shock 27kDa protein 1 antibody|Heat shock 28kDa protein 1 antibody|Heat Shock Protein 27 antibody|Heat shock protein beta 1 antibody|Heat shock protein beta-1 antibody|heat shock protein family B (small) member 1 antibody|HEL-S-102 antibody|HMN2B antibody|HS.76067 antibody|Hsp 25 antibody|HSP 27 antibody|Hsp 28 antibody|Hsp B1 antibody|Hsp25 antibody|HSP27 antibody|Hsp28 antibody|HspB1 antibody|HSPB1_HUMAN antibody|SRP27 antibody|Stress responsive protein 27 antibody|Stress-responsive protein 27 antibody|Anti-Hsp27 antibody [G3.1] (ab2790)

SCBT cat No: sc-1048|sc-13132|sc-59562|sc-9012|sc-51956|sc-51958|sc-1049|sc-135943|sc-398766|sc-1800|sc-28845|sc-1801|sc-376544|sc-47051|sc-135152|


Rabbit Polyclonal Phospho-HSPB1-S82 antibody

Catalogue No.





A phospho specific peptide corresponding to residues surrounding S82 of human HSPB1











Molecular weight



Phospho-HSPB1-S82 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


Affinity purification


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CMT2F antibody; HMN2B antibody; HSP27 antibody; HSP28 antibody; Hsp25 antibody; SRP27 antibody; HS.76067 antibody;

Protein names

CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067;

Protein function

Involved in stress resistance and actin organization.

Protein tissue specificity

Detected in all tissues tested: skeletal muscle, heart, aorta, large intestine, small intestine, stomach, esophagus, bladder, adrenal gland, thyroid, pancreas, testis, adipose tissue, kidney, liver, spleen, cerebral cortex, blood serum and cerebrospinal fluid. Highest levels are found in the heart and in tissues composed of striated and smooth muscle.

Protein sequence and domain

Belongs to the small heat shock protein (HSP20) family.

Protein post-translational modifications

Phosphorylated in MCF-7 cells on exposure to protein kinase C activators and heat shock.; Phosphorylation by MAPKAPK2 and MAPKAPK3 in response to stress leads to dissociate HSP27/HSPB1 from large small heat-shock protein (sHsps) oligomers and impair its chaperone activity and ability to protect against oxidative stress effectively. Phosphorylation by MAPKAPK5 in response to PKA stimulation induces F-actin rearrangement.

Protein cellular localization

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.


The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).

Research area

<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Signaling-Intermediates/">Signaling Intermediates</a>><a href="http://antibodyplus.com/product-tag/HSP/">HSP</a><br><a href="http://antibodyplus.com/product-tag/Signaling-Intermediates/"&gt; (View all antibody categories related to Signaling Intermediates)</a>


AntibodyPlus can customize Phospho-HSPB1-S82 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


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