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Rabbit Polyclonal Phospho-IL-10Ralpha (Y496) antibody (STJ90528)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:20000;
Recommended protocols: check protocols
Click or hover above images to see image description for IL-10Ralpha (phospho Tyr496) Polyclonal Antibody.
Check alternative names for the antibodyExpand
IL10RA antibody, IL10R antibody,||
SCBT cat No: To be updated
IL-10Ralpha (phospho Tyr496) Polyclonal Antibody
|Catalogue No.|| |
Phospho-IL-10Ralpha (Y496) Polyclonal Antibody detects endogenous levels of IL-10Ralpha protein only when phosphorylated at Y496.
Synthesized phospho-peptide derived from IL-10Ralpha (phospho Tyr496) at AA range 440-520
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:20000;
|Molecular weight|| |
IL-10Ralpha (phospho Tyr496) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
IL-10Ralpha (phospho Tyr496) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Interleukin-10 receptor subunit alpha antibody, IL-10 receptor subunit alpha antibody, IL-10R subunit alpha antibody, IL-10RA antibody, CDw210a antibody, Interleukin-10 receptor subunit 1 antibody, IL-10R subunit 1 antibody, IL-10R1 antibody, CD antigen CD210 antibody
|Protein names|| |
Interleukin-10 receptor subunit alpha , IL-10 receptor subunit alpha , IL-10R subunit alpha , IL-10RA , CDw210a , Interleukin-10 receptor subunit 1 , IL-10R subunit 1 , IL-10R1 , CD antigen CD210
|Protein function|| |
Receptor for IL10; binds IL10 with a high affinity.
|Protein tissue specificity|| |
Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.
|Involvement in disease|| |
Inflammatory bowel disease 28 (IBD28) [MIM:613148]: A chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the type II cytokine receptor family.
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein
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St John’s Laboratory Ltd.
|Product type|| |
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