Rabbit Polyclonal Phospho-IL-10Ralpha (Y496) antibody (STJ90528)

$99.00$319.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-IL-10Ralpha (Y496) antibody (STJ90528)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:20000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for IL-10Ralpha (phospho Tyr496) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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IL10RA antibody, IL10R antibody,||
SCBT cat No: To be updated

 

Name

IL-10Ralpha (phospho Tyr496) Polyclonal Antibody

Catalogue No.

STJ90528

Reactivity

Human

Specificity

Phospho-IL-10Ralpha (Y496) Polyclonal Antibody detects endogenous levels of IL-10Ralpha protein only when phosphorylated at Y496.

Immunogen

Synthesized phospho-peptide derived from IL-10Ralpha (phospho Tyr496) at AA range 440-520

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:20000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

63 kDa

Formulation

IL-10Ralpha (phospho Tyr496) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

IL-10Ralpha (phospho Tyr496) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Interleukin-10 receptor subunit alpha antibody, IL-10 receptor subunit alpha antibody, IL-10R subunit alpha antibody, IL-10RA antibody, CDw210a antibody, Interleukin-10 receptor subunit 1 antibody, IL-10R subunit 1 antibody, IL-10R1 antibody, CD antigen CD210 antibody

Database links

Human UniProt/Swiss-Prot:Q13651;Mouse UniPort/Swiss-Prot: Q61727;Rat UniProt/Swiss-Port: G3V830;Human Entrez Gene: 3587;Mouse Entrez Gene: 16154;Rat Entrez Gene: Rn.27718

Protein names

Interleukin-10 receptor subunit alpha , IL-10 receptor subunit alpha , IL-10R subunit alpha , IL-10RA , CDw210a , Interleukin-10 receptor subunit 1 , IL-10R subunit 1 , IL-10R1 , CD antigen CD210

Protein function

Receptor for IL10; binds IL10 with a high affinity.

Protein tissue specificity

Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.

Involvement in disease

Inflammatory bowel disease 28 (IBD28) [MIM:613148]: A chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the type II cytokine receptor family.

Protein cellular localization

Membrane; Single-pass type I membrane protein

Research area

All research areas>Membrane Receptors>IL-10R
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize IL-10Ralpha (phospho Tyr496) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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