Rabbit Polyclonal Phospho-IL10RA-S319/S323 antibody (AP0370)

$99.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-IL10RA-S319/S323 antibody (AP0370)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit Polyclonal Phospho-IL10RA-S319/S323 antibody.

Alternative names:

Check alternative names for the antibody

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CD210 antibody; IL10R antibody; CD210a antibody; CDW210A antibody; HIL-10R antibody; IL-10R1 antibody;
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SCBT cat No:

Name

Rabbit Polyclonal Phospho-IL10RA-S319/S323 antibody

Catalogue No.

AP0370

Reactivity

Human

Immunogen

A phospho specific peptide corresponding to residues surrounding S319/S323 of human IL10RA

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

63kDa

Formulation

Phospho-IL10RA-S319/S323 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CD210 antibody; IL10R antibody; CD210a antibody; CDW210A antibody; HIL-10R antibody; IL-10R1 antibody;

Protein names

CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1;

Protein function

Receptor for IL10; binds IL10 with a high affinity.

Protein tissue specificity

Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.

Protein sequence and domain

Belongs to the type II cytokine receptor family.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Background

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Note

AntibodyPlus can customize Phospho-IL10RA-S319/S323 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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