Rabbit Polyclonal Phospho-Intestinal Cell Kinase (Y159) antibody (STJ90581)

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Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-Intestinal Cell Kinase (Y159) antibody (STJ90581)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Intestinal Cell Kinase (phospho Tyr159) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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ICK antibody, KIAA0936 antibody,|2210420N10Rik antibody|MGC46090 antibody|mICK antibody|MRK antibody|OTTMUSP00000041856 antibody|OTTMUSP00000041857 antibody|Serine/threonine protein kinase ICK antibody|Anti-ICK antibody – N-terminal (ab194411)
SCBT cat No: sc-48020|sc-365244|

 

Name

Intestinal Cell Kinase (phospho Tyr159) Polyclonal Antibody

Catalogue No.

STJ90581

Reactivity

Human, Mouse, Rat

Specificity

Phospho-Intestinal Cell Kinase (Y159) Polyclonal Antibody detects endogenous levels of Intestinal Cell Kinase protein only when phosphorylated at Y159.

Immunogen

Synthesized phospho-peptide derived from Intestinal Cell Kinase (phospho Tyr159) at AA range 100-180

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

71 kDa

Formulation

Intestinal Cell Kinase (phospho Tyr159) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Intestinal Cell Kinase (phospho Tyr159) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Serine/threonine-protein kinase ICK antibody, Intestinal cell kinase antibody, hICK antibody, Laryngeal cancer kinase 2 antibody, LCK2 antibody, MAK-related kinase antibody, MRK antibody

Database links

Human UniProt/Swiss-Prot:Q9UPZ9;Mouse UniPort/Swiss-Prot: Q9JKV2;Rat UniProt/Swiss-Port: Q62726;Human Entrez Gene: 22858;Mouse Entrez Gene: 56542;Rat Entrez Gene: Rn.3750

Protein names

Serine/threonine-protein kinase ICK , Intestinal cell kinase , hICK , Laryngeal cancer kinase 2 , LCK2 , MAK-related kinase , MRK

Protein function

Required for ciliogenesis . Phosphorylates KIF3A (By similarity). Involved in the control of ciliary length . Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity). May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity). / ATP + a protein = ADP + a phosphoprotein. / Mg2+

Protein tissue specificity

Expressed in heart, brain, placenta, pancreas, thymus, prostate, testis, ovary, small intestine and colon, with highest levels in placenta and testis. Not detected in spleen. Also expressed in many cancer cell lines.

Involvement in disease

Endocrine-cerebroosteodysplasia (ECO) [MIM:612651]: Previously unidentified neonatal lethal recessive disorder with multiple anomalies involving the endocrine, cerebral, and skeletal systems. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. / Contains 1 protein kinase domain.

Protein post-translational modifications

Autophosphorylated on serine and threonine residues. May play a role in enzyme activation.

Protein cellular localization

Nucleus / Cytoplasm > cytosol / Cell projection > cilium / Cytoplasm > cytoskeleton > cilium basal body

Research area

All research areas>Kinases and Phosphatases>Intestinal Cell Kinase
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize Intestinal Cell Kinase (phospho Tyr159) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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