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Rabbit Polyclonal Phospho-Intestinal Cell Kinase (Y159) antibody (STJ90581)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000;
Recommended protocols: check protocols
Click or hover above images to see image description for Intestinal Cell Kinase (phospho Tyr159) Polyclonal Antibody.
Check alternative names for the antibodyExpand
ICK antibody, KIAA0936 antibody,|2210420N10Rik antibody|MGC46090 antibody|mICK antibody|MRK antibody|OTTMUSP00000041856 antibody|OTTMUSP00000041857 antibody|Serine/threonine protein kinase ICK antibody|Anti-ICK antibody – N-terminal (ab194411)
SCBT cat No: sc-48020|sc-365244|
Intestinal Cell Kinase (phospho Tyr159) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-Intestinal Cell Kinase (Y159) Polyclonal Antibody detects endogenous levels of Intestinal Cell Kinase protein only when phosphorylated at Y159.
Synthesized phospho-peptide derived from Intestinal Cell Kinase (phospho Tyr159) at AA range 100-180
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000;
|Molecular weight|| |
Intestinal Cell Kinase (phospho Tyr159) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Intestinal Cell Kinase (phospho Tyr159) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Serine/threonine-protein kinase ICK antibody, Intestinal cell kinase antibody, hICK antibody, Laryngeal cancer kinase 2 antibody, LCK2 antibody, MAK-related kinase antibody, MRK antibody
|Protein names|| |
Serine/threonine-protein kinase ICK , Intestinal cell kinase , hICK , Laryngeal cancer kinase 2 , LCK2 , MAK-related kinase , MRK
|Protein function|| |
Required for ciliogenesis . Phosphorylates KIF3A (By similarity). Involved in the control of ciliary length . Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity). May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity). / ATP + a protein = ADP + a phosphoprotein. / Mg2+
|Protein tissue specificity|| |
Expressed in heart, brain, placenta, pancreas, thymus, prostate, testis, ovary, small intestine and colon, with highest levels in placenta and testis. Not detected in spleen. Also expressed in many cancer cell lines.
|Involvement in disease|| |
Endocrine-cerebroosteodysplasia (ECO) [MIM:612651]: Previously unidentified neonatal lethal recessive disorder with multiple anomalies involving the endocrine, cerebral, and skeletal systems. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. / Contains 1 protein kinase domain.
|Protein post-translational modifications|| |
Autophosphorylated on serine and threonine residues. May play a role in enzyme activation.
|Protein cellular localization|| |
Nucleus / Cytoplasm > cytosol / Cell projection > cilium / Cytoplasm > cytoskeleton > cilium basal body
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St John’s Laboratory Ltd.
|Product type|| |
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