Rabbit Polyclonal Phospho-Ksr-1 (S392) antibody (STJ90763)

$99.00$319.00

Reactivity: Human, Mouse
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-Ksr-1 (S392) antibody (STJ90763)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Ksr-1 (phospho Ser392) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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KSR1 antibody, KSR antibody,|BKSR 1 antibody|BKSR1 antibody|dKsr antibody|EK 31 antibody|EK31 antibody|hb antibody|Kinase suppressor of Ras 1 antibody|Kinase suppressor of ras antibody|KSR 1 antibody|KSR antibody|KSR1 antibody|KSR1_HUMAN antibody|Positive Ras signaling mediator family member (86.4 kD) antibody|Positive Ras signaling mediator family member antibody|RSU 2 antibody|RSU2 antibody|SR 31 antibody|SR31 antibody|Suppressor of activated let 60 Ras SUR3 antibody|Suppressor of Ras1 31 antibody|Anti-KSR1 antibody [EPR2421Y] (ab68483)
SCBT cat No: sc-9317|sc-25416|sc-1837|sc-56923|

 

Name

Ksr-1 (phospho Ser392) Polyclonal Antibody

Catalogue No.

STJ90763

Reactivity

Human, Mouse

Specificity

Phospho-Ksr-1 (S392) Polyclonal Antibody detects endogenous levels of Ksr-1 protein only when phosphorylated at S392.

Immunogen

Synthesized phospho-peptide derived from Ksr-1 (phospho Ser392) at AA range 330-410

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

115 kDa

Formulation

Ksr-1 (phospho Ser392) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Ksr-1 (phospho Ser392) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Kinase suppressor of Ras 1 antibody

Database links

Human UniProt/Swiss-Prot:Q8IVT5;Mouse UniPort/Swiss-Prot: Q61097;Rat UniProt/Swiss-Port: D3ZHL1;Human Entrez Gene: 8844;Mouse Entrez Gene: 16706;Rat Entrez Gene: Rn.12903

Protein names

Kinase suppressor of Ras 1

Protein function

Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.

Protein sequence and domain

The protein kinase domain is predicted to be catalytically inactive. The domain is sufficient for KSR1 and KSR1-mediated MAP2K1 and MAP2K2 membrane localization. The domain is required but not sufficient for MAP kinase-mediated inhibition of ELK1 phosphorylation (PubMed:10409742). / Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. / Contains 1 phorbol-ester/DAG-type zinc finger. / Contains 1 protein kinase domain.

Protein post-translational modifications

Phosphorylated on Ser-311 and, to a higher extent, on Ser-406 by MARK3. Dephosphorylated on Ser-406 by PPP2CA. In resting cells, phosphorylated KSR1 is cytoplasmic and in stimulated cells, dephosphorylated KSR1 is membrane-associated (By similarity).

Protein cellular localization

Cytoplasm / Membrane / Peripheral membrane protein / Endoplasmic reticulum membrane

Research area

All research areas>Kinases and Phosphatases>Ksr
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize Ksr-1 (phospho Ser392) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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