Rabbit Polyclonal Phospho-MAK (Y159) antibody (STJ90583)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-MAK (Y159) antibody (STJ90583)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:40000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for MAK (phospho Tyr159) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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MAK antibody,|intestinal cell kinase antibody|dJ417M14.2 antibody|fj04c02 antibody|Ick antibody|Mak antibody|MAK_HUMAN antibody|Male germ cell associated kinase antibody|Male germ cell-associated kinase antibody|male germ cell-associated kinase retinal-enriched isoform antibody|OTTHUMP00000016025 antibody|Rck antibody|RP62 antibody|Serine/threonine protein kinase MAK antibody|Serine/threonine-protein kinase MAK antibody|testicular secretory protein Li 28 antibody|wu:fj04c02 antibody|zgc:56603 antibody|Anti-MAK antibody (ab80536)
SCBT cat No: To be updated

 

Name

MAK (phospho Tyr159) Polyclonal Antibody

Catalogue No.

STJ90583

Reactivity

Human, Mouse, Rat

Specificity

Phospho-MAK (Y159) Polyclonal Antibody detects endogenous levels of MAK protein only when phosphorylated at Y159.

Immunogen

Synthesized phospho-peptide derived from MAK (phospho Tyr159) at AA range 100-180

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:40000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

85 kDa

Formulation

MAK (phospho Tyr159) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

MAK (phospho Tyr159) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Serine/threonine-protein kinase MAK antibody, Male germ cell-associated kinase antibody

Database links

Human UniProt/Swiss-Prot:P20794;Mouse UniPort/Swiss-Prot: Q04859;Rat UniProt/Swiss-Port: P20793;Human Entrez Gene: 4117;Mouse Entrez Gene: 17152;Rat Entrez Gene: Rn.9670

Protein names

Serine/threonine-protein kinase MAK , Male germ cell-associated kinase

Protein function

Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors (By similarity). Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells. / ATP + a protein = ADP + a phosphoprotein.

Protein tissue specificity

Expressed in prostate cancer cell lines at generally higher levels than in normal prostate epithelial cell lines. Isoform 1 is expressed in kidney, testis, lung, trachea, and retina. Isoform 2 is retina-specific where it is expressed in rod and cone photoreceptors.

Involvement in disease

Retinitis pigmentosa 62 (RP62) [MIM:614181]: A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. / Contains 1 protein kinase domain.

Protein post-translational modifications

Autophosphorylated. Phosphorylated on serine and threonine residues.

Protein cellular localization

Nucleus / Cytoplasm > cytoskeleton > microtubule organizing center > centrosome / Cytoplasm > cytoskeleton > spindle / Midbody / Cell projection > cilium > photoreceptor outer segment / Photoreceptor inner segment

Research area

All research areas>Kinases and Phosphatases>MAK
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize MAK (phospho Tyr159) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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