Rabbit Polyclonal Phospho-MCM4 (S54) antibody (STJ90514)

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Reactivity: Human, Mouse, Monkey
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-MCM4 (S54) antibody (STJ90514)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for MCM4 (phospho Ser54) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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MCM4 antibody, CDC21 antibody,|19G antibody|AI325074 antibody|AU045576 antibody|CDC 21 antibody|CDC 54 antibody|CDC21 antibody|CDC21 homolog antibody|CDC21, S. pombe, homolog of antibody|CDC54 antibody|Cell division cycle 21, S. pombe, homolog of antibody|DNA replication licensing factor MCM 4 antibody|DNA replication licensing factor MCM4 antibody|hCdc 21 antibody|hCdc21 antibody|Homolog of S. pombe cell devision cycle 21 antibody|KIAA4003 antibody|mcdc21 antibody|MCM 4 antibody|MCM 4 minichromosome maintenance deficient 4 antibody|mcm4 antibody|MCM4 minichromosome maintenance deficient 4 antibody|MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) antibody|MCM4_HUMAN antibody|Mcmd4 antibody|MGC33310 antibody|Minichromosome maintenance 4 antibody|Minichromosome maintenance complex component 4 antibody|Minichromosome maintenance deficient (S. cerevisiae) 4 antibody|Minichromosome maintenance deficient 4 antibody|Minichromosome maintenance deficient 4 homolog (S. cerevisiae) antibody|Minichromosome maintenance, S. cerevisiae, homolog of, 4 antibody|mKIAA4003 antibody|NKCD antibody|NKGCD antibody|P1 CDC21 antibody|P1-CDC21 antibody|P1CDC21 antibody|Anti-MCM4 antibody (ab4459)
SCBT cat No: sc-48407|sc-9840|sc-28317|sc-22779|

 

Name

MCM4 (phospho Ser54) Polyclonal Antibody

Catalogue No.

STJ90514

Reactivity

Human, Mouse, Monkey

Specificity

Phospho-MCM4 (S54) Polyclonal Antibody detects endogenous levels of MCM4 protein only when phosphorylated at S54.

Immunogen

Synthesized phospho-peptide derived from MCM4 (phospho Ser54) at AA range 30-110

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

85 kDa

Formulation

MCM4 (phospho Ser54) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

MCM4 (phospho Ser54) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

DNA replication licensing factor MCM4 antibody, CDC21 homolog antibody, P1-CDC21 antibody

Database links

Human UniProt/Swiss-Prot:P33991;Mouse UniPort/Swiss-Prot: P49717;Rat UniProt/Swiss-Port: G3V681;Human Entrez Gene: 4173;Mouse Entrez Gene: 17217;Rat Entrez Gene: Rn.8341

Protein names

DNA replication licensing factor MCM4 , CDC21 homolog , P1-CDC21

Protein function

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ‘once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. / ATP + H2O = ADP + phosphate.

Involvement in disease

Natural killer cell and glucocorticoid deficiency with DNA repair defect (NKGCD) [MIM:609981]: An autosomal recessive disorder characterized by severe intra- and extrauterine growth retardation, microcephaly, decreased numbers of natural killer cells, and recurrent viral infections, most often affecting the respiratory tract and leading to respiratory failure. Affected individuals also have adrenal insufficiency requiring corticosteroid replacement therapy and may have an increased susceptibility to cancer. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the MCM family. / Contains 1 MCM domain.

Protein post-translational modifications

Sumoylated; SUMO2 modified in response to stress caused by inhibition of proteasome activity (in vitro).

Protein cellular localization

Nucleus

Research area

All research areas>Cell Cycle Proteins>MCM
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize MCM4 (phospho Ser54) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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