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Rabbit Polyclonal Phospho-MCM4 (S54) antibody (STJ90514)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;
Recommended protocols: check protocols
Click or hover above images to see image description for MCM4 (phospho Ser54) Polyclonal Antibody.
Check alternative names for the antibodyExpand
MCM4 antibody, CDC21 antibody,|19G antibody|AI325074 antibody|AU045576 antibody|CDC 21 antibody|CDC 54 antibody|CDC21 antibody|CDC21 homolog antibody|CDC21, S. pombe, homolog of antibody|CDC54 antibody|Cell division cycle 21, S. pombe, homolog of antibody|DNA replication licensing factor MCM 4 antibody|DNA replication licensing factor MCM4 antibody|hCdc 21 antibody|hCdc21 antibody|Homolog of S. pombe cell devision cycle 21 antibody|KIAA4003 antibody|mcdc21 antibody|MCM 4 antibody|MCM 4 minichromosome maintenance deficient 4 antibody|mcm4 antibody|MCM4 minichromosome maintenance deficient 4 antibody|MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) antibody|MCM4_HUMAN antibody|Mcmd4 antibody|MGC33310 antibody|Minichromosome maintenance 4 antibody|Minichromosome maintenance complex component 4 antibody|Minichromosome maintenance deficient (S. cerevisiae) 4 antibody|Minichromosome maintenance deficient 4 antibody|Minichromosome maintenance deficient 4 homolog (S. cerevisiae) antibody|Minichromosome maintenance, S. cerevisiae, homolog of, 4 antibody|mKIAA4003 antibody|NKCD antibody|NKGCD antibody|P1 CDC21 antibody|P1-CDC21 antibody|P1CDC21 antibody|Anti-MCM4 antibody (ab4459)
SCBT cat No: sc-48407|sc-9840|sc-28317|sc-22779|
MCM4 (phospho Ser54) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Monkey
Phospho-MCM4 (S54) Polyclonal Antibody detects endogenous levels of MCM4 protein only when phosphorylated at S54.
Synthesized phospho-peptide derived from MCM4 (phospho Ser54) at AA range 30-110
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;
|Molecular weight|| |
MCM4 (phospho Ser54) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
MCM4 (phospho Ser54) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
DNA replication licensing factor MCM4 antibody, CDC21 homolog antibody, P1-CDC21 antibody
|Protein names|| |
DNA replication licensing factor MCM4 , CDC21 homolog , P1-CDC21
|Protein function|| |
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ‘once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. / ATP + H2O = ADP + phosphate.
|Involvement in disease|| |
Natural killer cell and glucocorticoid deficiency with DNA repair defect (NKGCD) [MIM:609981]: An autosomal recessive disorder characterized by severe intra- and extrauterine growth retardation, microcephaly, decreased numbers of natural killer cells, and recurrent viral infections, most often affecting the respiratory tract and leading to respiratory failure. Affected individuals also have adrenal insufficiency requiring corticosteroid replacement therapy and may have an increased susceptibility to cancer. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the MCM family. / Contains 1 MCM domain.
|Protein post-translational modifications|| |
Sumoylated; SUMO2 modified in response to stress caused by inhibition of proteasome activity (in vitro).
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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