Rabbit Polyclonal Phospho-MEK Kinase-1 (T1402) antibody (STJ90946)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-MEK Kinase-1 (T1402) antibody (STJ90946)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for MEK Kinase-1 (phospho Thr1402) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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MAP3K1 antibody, MAPKKK1 antibody, MEKK antibody, MEKK1 antibody,|M3K1_HUMAN antibody|MAP3K1 antibody|MAPK/ERK kinase kinase 1 antibody|MAPKKK1 antibody|MEK kinase 1 antibody|MEKK 1 antibody|Mekk antibody|MEKK1 antibody|Mitogen activated protein kinase kinase kinase 1 antibody|Mitogen activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase antibody|Mitogen-activated protein kinase kinase kinase 1 antibody|SRXY6 antibody|Anti-MEKK1 antibody [2F6] – BSA and Azide free (ab212601)
SCBT cat No: sc-449|sc-448|sc-252|sc-17820|sc-49449|sc-398091|

 

Name

MEK Kinase-1 (phospho Thr1402) Polyclonal Antibody

Catalogue No.

STJ90946

Reactivity

Human, Mouse, Rat

Specificity

Phospho-MEK Kinase-1 (T1402) Polyclonal Antibody detects endogenous levels of MEK Kinase-1 protein only when phosphorylated at T1402.

Immunogen

Synthesized phospho-peptide derived from MEK Kinase-1 (phospho Thr1402) at AA range 1340-1420

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

130 kDa

Formulation

MEK Kinase-1 (phospho Thr1402) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

MEK Kinase-1 (phospho Thr1402) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Mitogen-activated protein kinase kinase kinase 1 antibody, MAPK/ERK kinase kinase 1 antibody, MEK kinase 1 antibody, MEKK 1 antibody

Database links

Human UniProt/Swiss-Prot:Q13233;Rat UniProt/Swiss-Port: Q62925;Human Entrez Gene: 4214;Mouse Entrez Gene: 26401;Rat Entrez Gene: Rn.11081

Protein names

Mitogen-activated protein kinase kinase kinase 1 , MAPK/ERK kinase kinase 1 , MEK kinase 1 , MEKK 1

Protein function

Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway. / ATP + a protein = ADP + a phosphoprotein. / Mg2+ / Activated by autophosphorylation on Thr-1400 and Thr-1412 following oligomerization.

Involvement in disease

46,XY sex reversal 6 (SRXY6) [MIM:613762]: A disorder of sex development. Affected individuals have a 46,XY karyotype but present as phenotypically normal females. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. / Contains 1 protein kinase domain. / Contains 1 RING-type zinc finger. / Contains 1 SWIM-type zinc finger.

Protein post-translational modifications

Autophosphorylated.

Research area

All research areas>Kinases and Phosphatases>MEK kinase-1
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize MEK Kinase-1 (phospho Thr1402) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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