Rabbit polyclonal Phospho-MKNK1-T197/202 antibody (AP0544)

$69.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal Phospho-MKNK1-T197/202 antibody (AP0544)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal Phospho-MKNK1-T197/202 antibody.

Alternative names:

Check alternative names for the antibody

Expand

MNK1 antibody
MAP kinase interacting kinase 1 antibody|MAP kinase interacting serine/threonine kinase 1 antibody|MAP kinase signal integrating kinase 1 antibody|MAP kinase signal-integrating kinase 1 antibody|MAP kinase-interacting serine/threonine-protein kinase 1 antibody|MAPK signal integrating kinase 1 antibody|MITOGEN-ACTIVATED PROTEIN KINASE-INTERACTING SERINE/THREONINE KINASE 1 antibody|mknk1 antibody|MKNK1_HUMAN antibody|MNK 1 antibody|Mnk1 antibody|Anti-MNK1 antibody (ab89223)

SCBT cat No: sc-133107|sc-6965|sc-133108|sc-133246|sc-28780|sc-6962|sc-271559|

Name

Rabbit polyclonal Phospho-MKNK1-T197/202 antibody

Catalogue No.

AP0544

Reactivity

Human

Immunogen

A phospho specific peptide corresponding to residues surrounding T197/202 of human MKNK1

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 51kDa/Observed: Refer to figures

Formulation

Phospho-MKNK1-T197/202 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Phospho-MKNK1-T197/202 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MNK1 antibody

Database links

Human UniProt/Swiss-Prot:Q9BUB5

Protein names

MNK1

Protein function

May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.

Protein tissue specificity

Ubiquitous.

Protein sequence and domain

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.; Contains 1 protein kinase domain.

Protein post-translational modifications

Dual phosphorylation of Thr-250 and Thr-255 activates the kinase. Phosphorylation of Thr-385 activates the kinase. MAPK3/ERK1 is one of the kinases which activate MKNK1/MNK1. Phosphorylation by PAK2 leads to a reduced phosphorylation of EIF4G1.

Protein cellular localization

Isoform 2: Cytoplasm.; Isoform 3: Cytoplasm. Nucleus.

Background

This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene.

Research area

All research areas>Kinases and Phosphatases>Mnk
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize Phospho-MKNK1-T197/202 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!