Rabbit Polyclonal Phospho-MKP-1/2 (S296/318) antibody (STJ90983)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-MKP-1/2 (S296/318) antibody (STJ90983)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for MKP-1/2 (phospho Ser296/318) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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DUSP1 antibody, CL100 antibody, MKP1 antibody, PTPN10 antibody, VH1 antibody,|CL 100 antibody|CL100 antibody|Dual Specificity Phosphatase 1 antibody|Dual specificity protein phosphatase 1 antibody|Dual specificity protein phosphatase hVH1 antibody|DUS1_HUMAN antibody|DUSP 1 antibody|Dusp1 antibody|HVH1 antibody|MAP kinase phosphatase 1 antibody|Mitogen-activated protein kinase phosphatase 1 antibody|MKP-1 antibody|MKP1 antibody|Protein tyrosine phosphatase CL100 antibody|Protein-tyrosine phosphatase CL100 antibody|PTPN10 antibody|Serine/threonine specific protein phosphatase antibody|VH1 antibody|Anti-DUSP1 antibody [EPR18884] (ab195261)
SCBT cat No: sc-370|sc-271684|sc-373841|sc-10796|sc-1102|sc-1199|

 

Name

MKP-1/2 (phospho Ser296/318) Polyclonal Antibody

Catalogue No.

STJ90983

Reactivity

Human, Mouse, Rat

Specificity

Phospho-MKP-1/2 (S296/318) Polyclonal Antibody detects endogenous levels of MKP-1/2 protein only when phosphorylated at S296/318.

Immunogen

Synthesized phospho-peptide derived from MKP-1/2 (phospho Ser296/318) at AA range 230-310

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

45 kDa

Formulation

MKP-1/2 (phospho Ser296/318) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

MKP-1/2 (phospho Ser296/318) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Dual specificity protein phosphatase 1 antibody, Dual specificity protein phosphatase hVH1 antibody, Mitogen-activated protein kinase phosphatase 1 antibody, MAP kinase phosphatase 1 antibody, MKP-1 antibody, Protein-tyrosine phosphatase CL100 antibody

Database links

Human UniProt/Swiss-Prot:P28562 ;Human Entrez Gene: 1843;

Protein names

Dual specificity protein phosphatase 1 , Dual specificity protein phosphatase hVH1 , Mitogen-activated protein kinase phosphatase 1 , MAP kinase phosphatase 1 , MKP-1 , Protein-tyrosine phosphatase CL100

Protein function

Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both ‘Thr-183’ and ‘Tyr-185’, regulating its activity during the meiotic cell cycle. / Protein tyrosine phosphate + H2O = protein tyrosine + phosphate. / [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Protein tissue specificity

Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.

Protein sequence and domain

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. / Contains 1 rhodanese domain. / Contains 1 tyrosine-protein phosphatase domain.

Protein post-translational modifications

Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation.

Protein cellular localization

Nucleus

Research area

All research areas>Kinases and Phosphatases>MKP-3
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize MKP-1/2 (phospho Ser296/318) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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