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Rabbit Polyclonal Phospho-Mnk1 (T385) antibody (STJ90984)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;
Recommended protocols: check protocols
Click or hover above images to see image description for Mnk1 (phospho Thr385) Polyclonal Antibody.
Check alternative names for the antibodyExpand
MKNK1 antibody, MNK1 antibody,|MAP kinase interacting kinase 1 antibody|MAP kinase interacting serine/threonine kinase 1 antibody|MAP kinase signal integrating kinase 1 antibody|MAP kinase signal-integrating kinase 1 antibody|MAP kinase-interacting serine/threonine-protein kinase 1 antibody|MAPK signal integrating kinase 1 antibody|MITOGEN-ACTIVATED PROTEIN KINASE-INTERACTING SERINE/THREONINE KINASE 1 antibody|mknk1 antibody|MKNK1_HUMAN antibody|MNK 1 antibody|Mnk1 antibody|Anti-MNK1 antibody (ab89223)
SCBT cat No: sc-133107|sc-6965|sc-133108|sc-133246|sc-28780|sc-6962|sc-271559|
Mnk1 (phospho Thr385) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-Mnk1 (T385) Polyclonal Antibody detects endogenous levels of Mnk1 protein only when phosphorylated at T385.
Synthesized phospho-peptide derived from Mnk1 (phospho Thr385) at AA range 320-400
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;
|Molecular weight|| |
Mnk1 (phospho Thr385) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Mnk1 (phospho Thr385) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
MAP kinase-interacting serine/threonine-protein kinase 1 antibody, MAP kinase signal-integrating kinase 1 antibody, MAPK signal-integrating kinase 1 antibody, Mnk1 antibody
|Protein names|| |
MAP kinase-interacting serine/threonine-protein kinase 1 , MAP kinase signal-integrating kinase 1 , MAPK signal-integrating kinase 1 , Mnk1
|Protein function|| |
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. / ATP + a protein = ADP + a phosphoprotein. / Mg2+ / Phosphorylated and activated by the p38 kinases and kinases in the Erk pathway.
|Protein tissue specificity|| |
|Protein sequence and domain|| |
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. / Contains 1 protein kinase domain.
|Protein post-translational modifications|| |
Dual phosphorylation of Thr-250 and Thr-255 activates the kinase. Phosphorylation of Thr-385 activates the kinase. MAPK3/ERK1 is one of the kinases which activate MKNK1/MNK1. Phosphorylation by PAK2 leads to a reduced phosphorylation of EIF4G1.
|Protein cellular localization|| |
Cytoplasm / Cytoplasm / Nucleus
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St John’s Laboratory Ltd.
|Product type|| |
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