Rabbit Polyclonal Phospho-MYL12A-S18 antibody (AP0412)

$99.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-MYL12A-S18 antibody (AP0412)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

MLCB antibody; MRCL3 antibody; MRLC3 antibody; MYL2B antibody;
ML12A_HUMAN antibody|MLC 2B antibody|MLC-2B antibody|MLCB antibody|MYL12A antibody|Myosin regulatory light chain 12A antibody|Myosin regulatory light chain 2 antibody|Myosin regulatory light chain 2, nonsarcomeric antibody|Myosin regulatory light chain MRCL3 antibody|Myosin regulatory light chain MRLC3 antibody|Myosin RLC antibody|Myosin, light polypeptide, regulatory, non sarcomeric (20kD) antibody|nonsarcomeric antibody|RLC antibody|Anti-MRCL3 antibody (ab131530)

SCBT cat No: sc-376606|sc-9449|sc-376677|sc-130331|sc-517205|

Name

Rabbit Polyclonal Phospho-MYL12A-S18 antibody

Catalogue No.

AP0412

Reactivity

Human, Mouse, Rat

Immunogen

A phospho specific peptide corresponding to residues surrounding S18 of human MYL12A

Host

Rabbit

Applications

WB, IHC

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

18kDa

Formulation

Phospho-MYL12A-S18 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MLCB antibody; MRCL3 antibody; MRLC3 antibody; MYL2B antibody;

Protein names

MLCB; MRCL3; MRLC3; MYL2B;

Protein function

Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity).

Protein sequence and domain

Contains 3 EF-hand domains.

Protein post-translational modifications

Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge (By similarity).

Background

This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.

Note

AntibodyPlus can customize Phospho-MYL12A-S18 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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