Rabbit Polyclonal Phospho-NFKBIE-S22 antibody (AP0212)

$99.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-NFKBIE-S22 antibody (AP0212)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

IKBE antibody;
I kappa B epsilon antibody|I-kappa-B-epsilon antibody|IkappaBepsilon antibody|IkB E antibody|IkB-E antibody|IkB-epsilon antibody|IKBE antibody|IKBE_HUMAN antibody|MGC72568 antibody|NF kappa B inhibitor epsilon antibody|NF kappa BIE antibody|NF-kappa-B inhibitor epsilon antibody|NF-kappa-BIE antibody|NFkappa BIE antibody|NFkappaB inhibitor epsilon antibody|NFKBIE antibody|Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor epsilon antibody|OTTHUMP00000016522 antibody|Slc35b2 antibody|solute carrier family 35, member B2 antibody|Anti-IKB epsilon antibody [EPR901(2)] (ab134143)

SCBT cat No: sc-135945|sc-324882|sc-373958|sc-374188|sc-365899|sc-7275|sc-7156|sc-7155|sc-33421|

Name

Rabbit Polyclonal Phospho-NFKBIE-S22 antibody

Catalogue No.

AP0212

Reactivity

Human, Mouse

Immunogen

A phospho specific peptide corresponding to residues surrounding S22 of human NFKBIE

Host

Rabbit

Applications

WB, IHC

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

40kDa

Formulation

Phospho-NFKBIE-S22 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

IKBE antibody;

Protein names

IKBE;

Protein function

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.

Protein tissue specificity

Highly expressed in spleen, testis and lung, followed by kidney, pancreas, heart, placenta and brain. Also expressed in granulocytes and macrophages.

Protein sequence and domain

Belongs to the NF-kappa-B inhibitor family.; Contains 6 ANK repeats.

Protein post-translational modifications

Serine phosphorylated; followed by proteasome-dependent degradation.

Protein cellular localization

Cytoplasm .

Background

The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus.

Research area

<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Transcription-Regulators/">Transcription Regulators</a>><a href="http://antibodyplus.com/product-tag/I-B/">I κ B</a><br><a href="http://antibodyplus.com/product-tag/Transcription-Regulators/"&gt; (View all antibody categories related to Transcription Regulators)</a>

Note

AntibodyPlus can customize Phospho-NFKBIE-S22 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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