Rabbit Polyclonal Phospho-Op18 (S16) antibody (STJ90357)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, IF, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-Op18 (S16) antibody (STJ90357)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Op18 (phospho Ser16) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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STMN1 antibody, C1orf215 antibody, LAP18 antibody, OP18 antibody,|C1orf215 antibody|Lag antibody|LAP 18 antibody|LAP18 antibody|Leukemia associated phosphoprotein p18 antibody|Leukemia-associated phosphoprotein p18 antibody|Metablastin antibody|Oncoprotein 18 antibody|OP 18 antibody|Op18 antibody|p18 antibody|p19 antibody|Phosphoprotein 19 antibody|Phosphoprotein p19 antibody|pp17 antibody|pp19 antibody|PR22 antibody|Pr22 protein antibody|Prosolin antibody|Protein Pr22 antibody|SMN antibody|Stathmin antibody|Stathmin1 antibody|STMN 1 antibody|Stmn1 antibody|STMN1_HUMAN antibody|Anti-Stathmin 1 antibody [EP1573Y] (ab52630)
SCBT cat No: sc-130333|sc-136010|sc-48362|sc-55531|sc-20796|sc-10899|sc-30573|sc-367890|sc-30572|sc-82004|

 

Name

Op18 (phospho Ser16) Polyclonal Antibody

Catalogue No.

STJ90357

Reactivity

Human, Mouse, Rat

Specificity

Phospho-Op18 (S16) Polyclonal Antibody detects endogenous levels of Op18 protein only when phosphorylated at S16.

Immunogen

Synthesized phospho-peptide derived from Op18 (phospho Ser16) at AA range 1-80

Host

Rabbit

Applications

WB, IHC, IF, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

17 kDa

Formulation

Op18 (phospho Ser16) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Op18 (phospho Ser16) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Stathmin antibody, Leukemia-associated phosphoprotein p18 antibody, Metablastin antibody, Oncoprotein 18 antibody, Op18 antibody, Phosphoprotein p19 antibody, pp19 antibody, Prosolin antibody, Protein Pr22 antibody, pp17 antibody

Database links

Human UniProt/Swiss-Prot:P16949;Mouse UniPort/Swiss-Prot: P54227;Rat UniProt/Swiss-Port: P13668;Human Entrez Gene: 3925;Mouse Entrez Gene: 16765;Rat Entrez Gene: Rn.555

Protein names

Stathmin , Leukemia-associated phosphoprotein p18 , Metablastin , Oncoprotein 18 , Op18 , Phosphoprotein p19 , pp19 , Prosolin , Protein Pr22 , pp17

Protein function

Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity).

Protein tissue specificity

Ubiquitous. Expression is strongest in fetal and adult brain, spinal cord, and cerebellum, followed by thymus, bone marrow, testis, and fetal liver. Expression is intermediate in colon, ovary, placenta, uterus, and trachea, and is readily detected at substantially lower levels in all other tissues examined. Lowest expression is found in adult liver. Present in much greater abundance in cells from patients with acute leukemia of different subtypes than in normal peripheral blood lymphocytes, non-leukemic proliferating lymphoid cells, bone marrow cells, or cells from patients with chronic lymphoid or myeloid leukemia.

Protein sequence and domain

Belongs to the stathmin family. / Contains 1 SLD (stathmin-like) domain.

Protein post-translational modifications

Many different phosphorylated forms are observed depending on specific combinations among the sites which can be phosphorylated. MAPK is responsible for the phosphorylation of stathmin in response to NGF. Phosphorylation at Ser-16 seems to be required for neuron polarization (By similarity). Phosphorylation at Ser-63 reduces tubulin binding 10-fold and suppresses the MT polymerization inhibition activity.

Protein cellular localization

Cytoplasm > cytoskeleton

Research area

All research areas>Signaling Intermediates>Op18
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize Op18 (phospho Ser16) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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