Rabbit Polyclonal Phospho-p47-phox (S304) antibody (STJ90364)

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Reactivity: Human, Monkey
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-p47-phox (S304) antibody (STJ90364)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for p47-phox (phospho Ser304) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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NCF1 antibody, NOXO2 antibody, SH3PXD1A antibody,|47 kDa autosomal chronic granulomatous disease protein antibody|47 kDa neutrophil oxidase factor antibody|NADPH oxidase organizer 2 antibody|NCF 47K antibody|NCF-1 antibody|NCF-47K antibody|Ncf1 antibody|NCF1_HUMAN antibody|Neutrophil cytosol factor 1 antibody|Neutrophil cytosolic factor 1 antibody|neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) antibody|Neutrophil NADPH oxidase factor 1 antibody|Nox organizer 2 antibody|Nox organizing protein 2 antibody|Nox-organizing protein 2 antibody|NOXO2 antibody|p47 phox antibody|p47-phox antibody|SH3 and PX domain containing protein 1A antibody|SH3 and PX domain-containing protein 1A antibody|SH3PXD1A antibody|Anti-NCF1 antibody (ab795)
SCBT cat No: sc-17844|sc-7660|sc-17845|sc-23492|sc-14015|

 

Name

p47-phox (phospho Ser304) Polyclonal Antibody

Catalogue No.

STJ90364

Reactivity

Human, Monkey

Specificity

Phospho-p47-phox (S304) Polyclonal Antibody detects endogenous levels of p47-phox protein only when phosphorylated at S304.

Immunogen

Synthesized phospho-peptide derived from p47-phox (phospho Ser304) at AA range 250-330

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

44 kDa

Formulation

p47-phox (phospho Ser304) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

p47-phox (phospho Ser304) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Neutrophil cytosol factor 1 antibody, NCF-1 antibody, 47 kDa autosomal chronic granulomatous disease protein antibody, 47 kDa neutrophil oxidase factor antibody, NCF-47K antibody, Neutrophil NADPH oxidase factor 1 antibody, Nox organizer 2 antibody, Nox-organizing protein 2 antibody, SH3 and PX domain-containing protein 1A antibody, p47-phox antibody

Database links

Human UniProt/Swiss-Prot:P14598;Mouse UniPort/Swiss-Prot: Q09014;Rat UniProt/Swiss-Port: Q811Y3;Human Entrez Gene: 653361;Mouse Entrez Gene: 17969;Rat Entrez Gene: Rn.38575

Protein names

Neutrophil cytosol factor 1 , NCF-1 , 47 kDa autosomal chronic granulomatous disease protein , 47 kDa neutrophil oxidase factor , NCF-47K , Neutrophil NADPH oxidase factor 1 , Nox organizer 2 , Nox-organizing protein 2 , SH3 and PX domain-containing protein 1A , p47-phox

Protein function

NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).

Protein tissue specificity

Detected in peripheral blood monocytes and neutrophils (at protein level).

Involvement in disease

Granulomatous disease, chronic, cytochrome-b-positive 1, autosomal recessive (CGD1) [MIM:233700]: A disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

The PX domain mediates interaction with phosphatidylinositol 3,4-bisphosphate and other anionic phospholipids. In the autoinhibited, unphosphorylated state an intramolecular interaction with the C-terminal SH3 domain precludes phospholipid binding and interaction with CYBA. Phosphorylation disrupts the autoinhibited state. / Contains 1 PX (phox homology) domain. / Contains 2 SH3 domains.

Protein post-translational modifications

Phosphorylated by PRKCD; phosphorylation induces activation of NCF1 and NADPH oxidase activity.

Protein cellular localization

Cytoplasm > cytosol / Membrane / Peripheral membrane protein / Cytoplasmic side

Research area

All research areas>Synthesis and Degradation>p47-phox
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize p47-phox (phospho Ser304) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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