Rabbit Polyclonal Phospho-PAK5/6 (S602/S560) antibody (STJ90635)

$99.00$319.00

Reactivity: Human, Mouse
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-PAK5/6 (S602/S560) antibody (STJ90635)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:20000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for PAK5/6 (phospho Ser602/S560) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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PAK7 antibody, KIAA1264 antibody, PAK5 antibody,|PAK4 antibody| PAK7 antibody|KIAA1142 antibody|KIAA126 antibody|p21-activated kinase 4 antibody|p21-activated kinase 5 antibody|p21-activated kinase 6 antibody|p21-activated kinase 7 antibody|PAK-4 antibody|PAK-5 antibody|PAK-6 antibody|PAK5 antibody|PAK6 antibody|Serine/threonine-protein kinase PAK 4 antibody|Serine/threonine-protein kinase PAK 6 antibody|Serine/threonine-protein kinase PAK 7 antibody|Phospho anti-PAK4 + PAK5 + PAK6 (S474 + S560 + S602) antibody [EPR2471(2)] (ab134097)
SCBT cat No: sc-393102|sc-32857|sc-393075|sc-25975|

 

Name

PAK5/6 (phospho Ser602/S560) Polyclonal Antibody

Catalogue No.

STJ90635

Reactivity

Human, Mouse

Specificity

Phospho-PAK5/6 (S602/S560) Polyclonal Antibody detects endogenous levels of PAK5/6 protein only when phosphorylated at S602/S560.

Immunogen

Synthesized phospho-peptide derived from PAK5/6 (phospho Ser602/S560) at AA range 540-620

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:20000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

75 kDa

Formulation

PAK5/6 (phospho Ser602/S560) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

PAK5/6 (phospho Ser602/S560) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Serine/threonine-protein kinase PAK 7 antibody, p21-activated kinase 5 antibody, PAK-5 antibody, p21-activated kinase 7 antibody, PAK-7 antibody

Database links

Human UniProt/Swiss-Prot:Q9P286 ;Human Entrez Gene: 57144;

Protein names

Serine/threonine-protein kinase PAK 7 , p21-activated kinase 5 , PAK-5 , p21-activated kinase 7 , PAK-7

Protein function

Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions. / ATP + a protein = ADP + a phosphoprotein.

Protein tissue specificity

Predominantly expressed in brain.

Protein sequence and domain

An autoinhibitory domain is present in the N-terminal region of the protein. / Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. / Contains 1 CRIB domain. / Contains 1 protein kinase domain.

Protein post-translational modifications

Autophosphorylated when activated by CDC42/p21.

Protein cellular localization

Mitochondrion / Cytoplasm / Nucleus

Research area

All research areas>Kinases and Phosphatases>PAK
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize PAK5/6 (phospho Ser602/S560) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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