Rabbit Polyclonal Phospho-Paxillin (Y118) antibody (STJ90379)

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Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-Paxillin (Y118) antibody (STJ90379)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Paxillin (phospho Tyr118) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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PXN antibody,|FLJ16691 antibody|FLJ23042 antibody|Paired box protein Pax 1 antibody|PAX 1 antibody|PAX1 antibody|PAXI_HUMAN antibody|Paxillin alpha antibody|Paxillin antibody|PXN antibody|PXN protein antibody|Anti-Paxillin antibody [Y113] (ab32084)
SCBT cat No: sc-136297|sc-390738|sc-365379|sc-373880|sc-393149|sc-7336|sc-365059|sc-365174|sc-5574|sc-31009|sc-31008|sc-31010|sc-390095|sc-367222|sc-166932|sc-271963|

 

Name

Paxillin (phospho Tyr118) Polyclonal Antibody

Catalogue No.

STJ90379

Reactivity

Human, Mouse, Rat

Specificity

Phospho-Paxillin (Y118) Polyclonal Antibody detects endogenous levels of Paxillin protein only when phosphorylated at Y118.

Immunogen

Synthesized phospho-peptide derived from Paxillin (phospho Tyr118) at AA range 50-130

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

64 kDa

Formulation

Paxillin (phospho Tyr118) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Paxillin (phospho Tyr118) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Paxillin antibody

Database links

Human UniProt/Swiss-Prot:P49023;Mouse UniPort/Swiss-Prot: Q8VI36;Rat UniProt/Swiss-Port: Q66H76;Human Entrez Gene: 5829;Mouse Entrez Gene: 19303;Rat Entrez Gene: Rn.75

Protein names

Paxillin

Protein function

Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).

Protein sequence and domain

Belongs to the paxillin family. / Contains 4 LIM zinc-binding domains.

Protein post-translational modifications

Phosphorylated by MAPK1/ERK2 (By similarity). Phosphorylated on tyrosine residues during integrin-mediated cell adhesion, embryonic development, fibroblast transformation and following stimulation of cells by mitogens. Phosphorylation at Ser-244 by CDK5 reduces its interaction with PTK2/FAK1 in matrix-cell focal adhesions (MCFA) during oligodendrocytes (OLs) differentiation. Phosphorylation at Tyr-31 and Tyr-118 by PTK6 promote the activation of RAC1 via CRK/CrKII, thereby promoting migration and invasion. Phosphorylation at Ser-250 by SLK is required for PXN redistribution and cell motility .

Protein cellular localization

Cytoplasm > cytoskeleton / Cell junction > focal adhesion / Cytoplasm > cell cortex

Research area

All research areas>Cell Adhesion Proteins>paxillin
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize Paxillin (phospho Tyr118) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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