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Rabbit Polyclonal Phospho-PEA-15 (S116) antibody (STJ90829)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
Recommended protocols: check protocols
Click or hover above images to see image description for PEA-15 (phospho Ser116) Polyclonal Antibody.
Check alternative names for the antibodyExpand
PEA15 antibody,|15 kDa phosphoprotein enriched in astrocytes antibody|Astrocytic phosphoprotein PEA 15 antibody|Astrocytic phosphoprotein PEA-15 antibody|Astrocytic phosphoprotein PEA15 antibody|HMAT 1 antibody|HMAT1 antibody|Homolog of mouse MAT 1 oncogene antibody|Homolog of mouse MAT1 oncogene antibody|HUMMAT 1H antibody|HUMMAT1H antibody|MAT 1 antibody|MAT 1H antibody|MAT1 antibody|MAT1H antibody|PEA 15 antibody|Pea15 antibody|PEA15 protein antibody|PEA15_HUMAN antibody|PED antibody|Phosphoprotein enriched in astrocytes 15 antibody|Phosphoprotein enriched in astrocytes 15kD antibody|Phosphoprotein enriched in diabetes antibody|Anti-PEA15 antibody – C-terminal (ab135694)
SCBT cat No: sc-166678|sc-28255|
PEA-15 (phospho Ser116) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat, Monkey
Phospho-PEA-15 (S116) Polyclonal Antibody detects endogenous levels of PEA-15 protein only when phosphorylated at S116.
Synthesized phospho-peptide derived from PEA-15 (phospho Ser116) at AA range 50-130
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
|Molecular weight|| |
PEA-15 (phospho Ser116) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PEA-15 (phospho Ser116) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Astrocytic phosphoprotein PEA-15 antibody, 15 kDa phosphoprotein enriched in astrocytes antibody, Phosphoprotein enriched in diabetes antibody, PED antibody
|Protein names|| |
Astrocytic phosphoprotein PEA-15 , 15 kDa phosphoprotein enriched in astrocytes , Phosphoprotein enriched in diabetes , PED
|Protein function|| |
Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.
|Protein tissue specificity|| |
Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose-producing tissues. Higher levels of expression are found in tissues from individuals with type 2 diabetes than in controls.
|Protein sequence and domain|| |
Contains 1 DED (death effector) domain.
|Protein post-translational modifications|| |
Phosphorylated by protein kinase C and calcium-calmodulin-dependent protein kinase. These phosphorylation events are modulated by neurotransmitters or hormones.
|Protein cellular localization|| |
AntibodyPlus can customize PEA-15 (phospho Ser116) Antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
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