Rabbit Polyclonal Phospho-PEA-15 (S116) antibody (STJ90829)

$99.00$319.00

Reactivity: Human, Mouse, Rat, Monkey
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-PEA-15 (S116) antibody (STJ90829)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for PEA-15 (phospho Ser116) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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PEA15 antibody,|15 kDa phosphoprotein enriched in astrocytes antibody|Astrocytic phosphoprotein PEA 15 antibody|Astrocytic phosphoprotein PEA-15 antibody|Astrocytic phosphoprotein PEA15 antibody|HMAT 1 antibody|HMAT1 antibody|Homolog of mouse MAT 1 oncogene antibody|Homolog of mouse MAT1 oncogene antibody|HUMMAT 1H antibody|HUMMAT1H antibody|MAT 1 antibody|MAT 1H antibody|MAT1 antibody|MAT1H antibody|PEA 15 antibody|Pea15 antibody|PEA15 protein antibody|PEA15_HUMAN antibody|PED antibody|Phosphoprotein enriched in astrocytes 15 antibody|Phosphoprotein enriched in astrocytes 15kD antibody|Phosphoprotein enriched in diabetes antibody|Anti-PEA15 antibody – C-terminal (ab135694)
SCBT cat No: sc-166678|sc-28255|

 

Name

PEA-15 (phospho Ser116) Polyclonal Antibody

Catalogue No.

STJ90829

Reactivity

Human, Mouse, Rat, Monkey

Specificity

Phospho-PEA-15 (S116) Polyclonal Antibody detects endogenous levels of PEA-15 protein only when phosphorylated at S116.

Immunogen

Synthesized phospho-peptide derived from PEA-15 (phospho Ser116) at AA range 50-130

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

15 kDa

Formulation

PEA-15 (phospho Ser116) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

PEA-15 (phospho Ser116) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Astrocytic phosphoprotein PEA-15 antibody, 15 kDa phosphoprotein enriched in astrocytes antibody, Phosphoprotein enriched in diabetes antibody, PED antibody

Database links

Human UniProt/Swiss-Prot:Q15121;Mouse UniPort/Swiss-Prot: Q62048;Rat UniProt/Swiss-Port: Q5U318;Human Entrez Gene: 8682;Mouse Entrez Gene: 18611;Rat Entrez Gene: Rn.155339

Protein names

Astrocytic phosphoprotein PEA-15 , 15 kDa phosphoprotein enriched in astrocytes , Phosphoprotein enriched in diabetes , PED

Protein function

Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.

Protein tissue specificity

Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose-producing tissues. Higher levels of expression are found in tissues from individuals with type 2 diabetes than in controls.

Protein sequence and domain

Contains 1 DED (death effector) domain.

Protein post-translational modifications

Phosphorylated by protein kinase C and calcium-calmodulin-dependent protein kinase. These phosphorylation events are modulated by neurotransmitters or hormones.

Protein cellular localization

Cytoplasm

Research area

All research areas>Tumor Suppressor/Apoptosis>PEA
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize PEA-15 (phospho Ser116) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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