Rabbit Polyclonal Phospho-PLCG2-Y753 antibody (AP0193)

$99.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-PLCG2-Y753 antibody (AP0193)

Supplier: ABclonal Inc.

Recommended applications: WB,IF

Recommended dilution:

WB 1:500 – 1:2000
IF 1:100 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit Polyclonal Phospho-PLCG2-Y753 antibody.

Alternative names:

Check alternative names for the antibody

Expand

FCAS3 antibody; APLAID antibody; RP11-510J16.3 antibody;
1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2 antibody|1-phosphatidylinositol-4 antibody|5-bisphosphate phosphodiesterase gamma-2 antibody|EC 3.1.4.11 antibody|Phosphoinositide phospholipase C antibody|Phosphoinositide phospholipase C-gamma-2 antibody|Phospholipase C gamma 2 antibody|Phospholipase C, gamma 2 (phosphatidylinositol specific) antibody|Phospholipase C-gamma-2 antibody|Phospholipase C-IV antibody|PLC 2 antibody|PLC gamma 2 antibody|PLC IV antibody|PLC-gamma-2 antibody|PLC-IV antibody|Plcg2 antibody|PLCG2_HUMAN antibody|Phospho anti-PLCG 2 (Y753) antibody (ab75659)

SCBT cat No: sc-390389|sc-5283|sc-9015|sc-407|sc-131752|

Name

Rabbit Polyclonal Phospho-PLCG2-Y753 antibody

Catalogue No.

AP0193

Reactivity

Human, Mouse, Rat

Immunogen

A phospho specific peptide corresponding to residues surrounding Y753 of human PLCG2

Host

Rabbit

Applications

WB, IF

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

150kDa

Formulation

Phospho-PLCG2-Y753 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

FCAS3 antibody; APLAID antibody; RP11-510J16.3 antibody;

Protein names

FCAS3; APLAID; RP11-510J16.3;

Protein function

The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

Protein sequence and domain

Contains 1 C2 domain.; Contains 1 PH domain.; Contains 1 PI-PLC X-box domain.; Contains 1 PI-PLC Y-box domain.; Contains 2 SH2 domains.; Contains 1 SH3 domain.

Protein post-translational modifications

Phosphorylated on tyrosine residues by CSF1R (By similarity). Phosphorylated on tyrosine residues by BTK and SYK; upon ligand-induced activation of a variety of growth factor receptors and immune system receptors. Phosphorylation leads to increased phospholipase activity.

Background

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane.

Research area

<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Synthesis-and-Degradation/">Synthesis and Degradation</a>><a href="http://antibodyplus.com/product-tag/PLC-gamma-2/">PLC gamma 2</a><br><a href="http://antibodyplus.com/product-tag/Synthesis-and-Degradation/"&gt; (View all antibody categories related to Synthesis and Degradation)</a>

Note

AntibodyPlus can customize Phospho-PLCG2-Y753 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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