Rabbit Polyclonal Phospho-PP2A-Calpha (Y307) antibody (STJ91049)


Reactivity: Human, Mouse, Rat
Applications: WB, IHC, IF, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Polyclonal Phospho-PP2A-Calpha (Y307) antibody (STJ91049)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for PP2A-Calpha (phospho Tyr307) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody


PPP2CA antibody,|PP2A alpha antibody|PP2A-alpha antibody|PP2AA_HUMAN antibody|PP2Aalpha antibody|PP2Ac antibody|PP2CA antibody|PP2Calpha antibody|PPP2CA antibody|Protein phosphatase 2 (formerly 2A) catalytic subunit alpha isoform antibody|Protein phosphatase 2 catalytic subunit alpha isoform antibody|Protein phosphatase 2, catalytic subunit, alpha isozyme antibody|Protein phosphatase 2A catalytic subunit, alpha isoform antibody|Replication protein C antibody|RP C antibody|RP-C antibody|RPC antibody|Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform antibody|Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody|Anti-PP2A-alpha antibody (ab137825)
SCBT cat No: sc-13601|sc-80990|sc-167616|sc-138914|sc-246424|sc-398374|sc-390685|sc-87080|sc-160276|sc-514660|sc-246432|



PP2A-Calpha (phospho Tyr307) Polyclonal Antibody

Catalogue No.



Human, Mouse, Rat


Phospho-PP2A-Calpha (Y307) Polyclonal Antibody detects endogenous levels of PP2A-Calpha protein only when phosphorylated at Y307.


Synthesized phospho-peptide derived from PP2A-Calpha (phospho Tyr307) at AA range 250-330





Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000;







Molecular weight

28 kDa


PP2A-Calpha (phospho Tyr307) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.


1 mg/ml


PP2A-Calpha (phospho Tyr307) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.


-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody, PP2A-alpha antibody, Replication protein C antibody, RP-C antibody

Database links

Human UniProt/Swiss-Prot:P67775;Mouse UniPort/Swiss-Prot: P63330;Rat UniProt/Swiss-Port: P63331;Human Entrez Gene: 5515;Mouse Entrez Gene: 19052;Rat Entrez Gene: Rn.1271

Protein names

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform , PP2A-alpha , Replication protein C , RP-C

Protein function

PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at ‘Ser-259’. / [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate. / Mn2+

Protein sequence and domain

Belongs to the PPP phosphatase family. PP-1 subfamily.

Protein post-translational modifications

Reversibly methyl esterified on Leu-309 by leucine carboxyl methyltransferase 1 (LCMT1) and protein phosphatase methylesterase 1 (PPME1). Carboxyl methylation influences the affinity of the catalytic subunit for the different regulatory subunits, thereby modulating the PP2A holoenzyme’s substrate specificity, enzyme activity and cellular localization. / Phosphorylation of either threonine (by autophosphorylation-activated protein kinase) or tyrosine results in inactivation of the phosphatase. Auto-dephosphorylation has been suggested as a mechanism for reactivation. / May be monoubiquitinated by NOSIP.

Protein cellular localization

Cytoplasm / Nucleus / Chromosome > centromere / Cytoplasm > cytoskeleton > spindle pole

Research area

All research areas>Kinases and Phosphatases>PP2A-C alpha / beta
(View all antibody categories related to Kinases and Phosphatases)


AntibodyPlus can customize PP2A-Calpha (phospho Tyr307) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.


St John’s Laboratory Ltd.

Product type

Primary antibody


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:

Welcome to AntibodyPlus!