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Rabbit polyclonal Phospho-RPS6KB1-S235/236 antibody (AP0538)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal Phospho-RPS6KB1-S235/236 antibody.
Check alternative names for the antibodyExpand
40S ribosomal protein S6 antibody|Air8 antibody|NP33 antibody|Phosphoprotein NP33 antibody|Pp30 antibody|Ribosomal protein S6 antibody|RP S6 antibody|rps6 antibody|RS6 antibody|RS6_HUMAN antibody|S6 antibody|S6 Ribosomal Protein antibody|Anti-RPS6 antibody (ab40820)
SCBT cat No: sc-293143|sc-293144|sc-293145|sc-514033|sc-101793|sc-54279|sc-86799|sc-86801|sc-69225|sc-393034|sc-69228|
Rabbit polyclonal Phospho-RPS6KB1-S235/236 antibody
|Catalogue No.|| |
A phospho specific peptide corresponding to residues surrounding S235/236 of human RPS6KB1
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 29kDa/Observed: Refer to Figures
Phospho-RPS6KB1-S235/236 antibody was tube-contained.
Phospho-RPS6KB1-S235/236 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.
|Protein sequence and domain|| |
Belongs to the ribosomal protein S6e family.
|Protein post-translational modifications|| |
Ribosomal protein S6 is the major substrate of protein kinases in eukaryote ribosomes. The phosphorylation is stimulated by growth factors, tumor promoting agents, and mitogens. It is dephosphorylated at growth arrest. Phosphorylated at Ser-235 and Ser-236 by RPS6KA1 and RPS6KA3; phosphorylation at these sites facilitates the assembly of the preinitiation complex.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
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