Rabbit polyclonal Phospho-RPS6KB1-S240/244 antibody (AP0537)

$69.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal Phospho-RPS6KB1-S240/244 antibody (AP0537)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal Phospho-RPS6KB1-S240/244 antibody.

Alternative names:

Check alternative names for the antibody

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S6 antibody
40S ribosomal protein S6 antibody|Air8 antibody|NP33 antibody|Phosphoprotein NP33 antibody|Pp30 antibody|Ribosomal protein S6 antibody|RP S6 antibody|rps6 antibody|RS6 antibody|RS6_HUMAN antibody|S6 antibody|S6 Ribosomal Protein antibody|Anti-RPS6 antibody (ab40820)

SCBT cat No: sc-293143|sc-293144|sc-293145|sc-514033|sc-101793|sc-54279|sc-86799|sc-86801|sc-69225|sc-393034|sc-69228|

Name

Rabbit polyclonal Phospho-RPS6KB1-S240/244 antibody

Catalogue No.

AP0537

Reactivity

Human

Immunogen

A phospho specific peptide corresponding to residues surrounding S240/244 of human RPS6KB1

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 29kDa/Observed: Refer to Figures

Formulation

Phospho-RPS6KB1-S240/244 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Phospho-RPS6KB1-S240/244 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

S6 antibody

Database links

Human UniProt/Swiss-Prot:P62753

Protein names

S6

Protein function

May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.

Protein sequence and domain

Belongs to the ribosomal protein S6e family.

Protein post-translational modifications

Ribosomal protein S6 is the major substrate of protein kinases in eukaryote ribosomes. The phosphorylation is stimulated by growth factors, tumor promoting agents, and mitogens. It is dephosphorylated at growth arrest. Phosphorylated at Ser-235 and Ser-236 by RPS6KA1 and RPS6KA3; phosphorylation at these sites facilitates the assembly of the preinitiation complex.

Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Research area

All research areas>Signaling Intermediates>Ribosomal Protein
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize Phospho-RPS6KB1-S240/244 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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