Rabbit Polyclonal Phospho-SLP-76 (Y128) antibody (STJ90961)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-SLP-76 (Y128) antibody (STJ90961)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for SLP-76 (phospho Tyr128) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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LCP2 antibody,|76 kDa tyrosine phosphoprotein antibody|CG8697 antibody|LCP 2 antibody|LCP2 antibody|LCP2_HUMAN antibody|Lymphocyte cytosolic protein 2 antibody|SH2 domain containing leukocyte protein 76 KD antibody|SH2 domain containing leukocyte protein of 76kD antibody|SH2 domain containing leukocyte protein of 76kDa antibody|SH2 domain-containing leukocyte protein of 76 kDa antibody|SLP 76 antibody|SLP 76 tyrosine phosphoprotein antibody|SLP-76 antibody|SLP-76 tyrosine phosphoprotein antibody|SLP76 antibody|SLP76 tyrosine phosphoprotein antibody|Anti-SLP76 antibody [EPR2549(2)] (ab109254)
SCBT cat No: To be updated

 

Name

SLP-76 (phospho Tyr128) Polyclonal Antibody

Catalogue No.

STJ90961

Reactivity

Human, Mouse, Rat

Specificity

Phospho-SLP-76 (Y128) Polyclonal Antibody detects endogenous levels of SLP-76 protein only when phosphorylated at Y128.

Immunogen

Synthesized phospho-peptide derived from SLP-76 (phospho Tyr128) at AA range 70-150

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

75 kDa

Formulation

SLP-76 (phospho Tyr128) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

SLP-76 (phospho Tyr128) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Lymphocyte cytosolic protein 2 antibody, SH2 domain-containing leukocyte protein of 76 kDa antibody, SLP-76 tyrosine phosphoprotein antibody, SLP76 antibody

Database links

Human UniProt/Swiss-Prot:Q13094;Mouse UniPort/Swiss-Prot: Q60787;Rat UniProt/Swiss-Port: Q920L0;Human Entrez Gene: 3937;Mouse Entrez Gene: 16822;Rat Entrez Gene: Rn.1057

Protein names

Lymphocyte cytosolic protein 2 , SH2 domain-containing leukocyte protein of 76 kDa , SLP-76 tyrosine phosphoprotein , SLP76

Protein function

Involved in T-cell antigen receptor mediated signaling.

Protein tissue specificity

Highly expressed in spleen, thymus and peripheral blood leukocytes. Highly expressed also in T-cell and monocytic cell lines, expressed at lower level in B-cell lines. Not detected in fibroblast or neuroblastoma cell lines.

Protein sequence and domain

The SH2 domain mediates interaction with phosphorylated CD6 (PubMed:16914752). The SH2 domain mediates interaction with SHB (PubMed:12084069). / Contains 1 SAM (sterile alpha motif) domain. / Contains 1 SH2 domain.

Protein post-translational modifications

Phosphorylated after T-cell receptor activation by ZAP70, ITK and TXK, which leads to the up-regulation of Th1 preferred cytokine IL-2. SYK-dependent phosphorylation is required for recruitment of PI3K signaling components.

Protein cellular localization

Cytoplasm

Research area

All research areas>Lymphocyte Signaling>SLP-76
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize SLP-76 (phospho Tyr128) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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