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Rabbit Polyclonal Phospho-SLP-76 (Y128) antibody (STJ90961)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
Recommended protocols: check protocols
Click or hover above images to see image description for SLP-76 (phospho Tyr128) Polyclonal Antibody.
Check alternative names for the antibodyExpand
LCP2 antibody,|76 kDa tyrosine phosphoprotein antibody|CG8697 antibody|LCP 2 antibody|LCP2 antibody|LCP2_HUMAN antibody|Lymphocyte cytosolic protein 2 antibody|SH2 domain containing leukocyte protein 76 KD antibody|SH2 domain containing leukocyte protein of 76kD antibody|SH2 domain containing leukocyte protein of 76kDa antibody|SH2 domain-containing leukocyte protein of 76 kDa antibody|SLP 76 antibody|SLP 76 tyrosine phosphoprotein antibody|SLP-76 antibody|SLP-76 tyrosine phosphoprotein antibody|SLP76 antibody|SLP76 tyrosine phosphoprotein antibody|Anti-SLP76 antibody [EPR2549(2)] (ab109254)
SCBT cat No: To be updated
SLP-76 (phospho Tyr128) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-SLP-76 (Y128) Polyclonal Antibody detects endogenous levels of SLP-76 protein only when phosphorylated at Y128.
Synthesized phospho-peptide derived from SLP-76 (phospho Tyr128) at AA range 70-150
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
|Molecular weight|| |
SLP-76 (phospho Tyr128) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
SLP-76 (phospho Tyr128) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Lymphocyte cytosolic protein 2 antibody, SH2 domain-containing leukocyte protein of 76 kDa antibody, SLP-76 tyrosine phosphoprotein antibody, SLP76 antibody
|Protein names|| |
Lymphocyte cytosolic protein 2 , SH2 domain-containing leukocyte protein of 76 kDa , SLP-76 tyrosine phosphoprotein , SLP76
|Protein function|| |
Involved in T-cell antigen receptor mediated signaling.
|Protein tissue specificity|| |
Highly expressed in spleen, thymus and peripheral blood leukocytes. Highly expressed also in T-cell and monocytic cell lines, expressed at lower level in B-cell lines. Not detected in fibroblast or neuroblastoma cell lines.
|Protein sequence and domain|| |
The SH2 domain mediates interaction with phosphorylated CD6 (PubMed:16914752). The SH2 domain mediates interaction with SHB (PubMed:12084069). / Contains 1 SAM (sterile alpha motif) domain. / Contains 1 SH2 domain.
|Protein post-translational modifications|| |
Phosphorylated after T-cell receptor activation by ZAP70, ITK and TXK, which leads to the up-regulation of Th1 preferred cytokine IL-2. SYK-dependent phosphorylation is required for recruitment of PI3K signaling components.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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