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Rabbit Polyclonal Phospho-Sox-9 (S181) antibody (STJ91055)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, IF, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000;
Recommended protocols: check protocols
Click or hover above images to see image description for Sox-9 (phospho Ser181) Polyclonal Antibody.
Check alternative names for the antibodyExpand
SOX9 antibody,|campomelic dysplasia autosomal sex reversal antibody|Transcription factor SOX 9 antibody|Transcription factor SOX-9 antibody|transcription factor SOX9 antibody|Anti-SOX9 antibody – ChIP Grade (ab3697)
SCBT cat No: To be updated
Sox-9 (phospho Ser181) Polyclonal Antibody
|Catalogue No.|| |
Phospho-Sox-9 (S181) Polyclonal Antibody detects endogenous levels of Sox-9 protein only when phosphorylated at S181.
Synthesized phospho-peptide derived from Sox-9 (phospho Ser181) at AA range 120-200
WB, IHC, IF, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000;
|Molecular weight|| |
Sox-9 (phospho Ser181) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Sox-9 (phospho Ser181) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Transcription factor SOX-9 antibody
|Protein names|| |
Transcription factor SOX-9
|Protein function|| |
Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.
|Involvement in disease|| |
Campomelic dysplasia (CMD1) [MIM:114290]: A rare, often lethal, osteochondrodysplasia characterized by congenital bowing and angulation of long bones. Other skeletal defects include unusually small scapula, deformed pelvis and spine, and a missing pair of ribs. Craniofacial and ear defects are common. Most patients die soon after birth due to respiratory distress which has been attributed to hypoplasia of the tracheobronchial cartilage and small thoracic cage. Up to two-thirds of affected XY individuals have genital defects or may develop as phenotypic females. . Note: The disease is caused by mutations affecting the gene represented in this entry.; 46,XX sex reversal 2 (SRXX2) [MIM:278850]: A condition in which male gonads develop in a genetic female (female to male sex reversal). . Note: The disease is caused by mutations affecting the gene represented in this entry.; 46,XY sex reversal 10 (SRXY10) [MIM:616425]: A disorder of sex development. Affected individuals have a 46,XY karyotype, show gonadal dysgenesis with streak gonads, look like normal females at birth, do not develop secondary sexual characteristics at puberty and do not menstruate. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Contains 1 HMG box DNA-binding domain.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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