Rabbit Polyclonal Phospho-STAM2 (Y192) antibody (STJ90559)

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Reactivity: Human, Mouse
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-STAM2 (Y192) antibody (STJ90559)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for STAM2 (phospho Tyr192) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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STAM2 antibody, HBP antibody,|DKFZp564C047 antibody|Hbp antibody|Hrs-binding protein antibody|HSE1 homolog antibody|Signal transducing adapter molecule 2 antibody|Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 antibody|Signal transducing adaptor molecule 2A antibody|Signal transducing adaptor molecule 2B antibody|Signal transducing adaptor molecule antibody|STAM like protein containing SH3 and ITAM domains 2 antibody|STAM-2 antibody|Stam2 antibody|STAM2_HUMAN antibody|STAM2A antibody|STAM2B antibody|Anti-STAM2 antibody [EPR8688] (ab151545)
SCBT cat No: To be updated

 

Name

STAM2 (phospho Tyr192) Polyclonal Antibody

Catalogue No.

STJ90559

Reactivity

Human, Mouse

Specificity

Phospho-STAM2 (Y192) Polyclonal Antibody detects endogenous levels of STAM2 protein only when phosphorylated at Y192.

Immunogen

Synthesized phospho-peptide derived from STAM2 (phospho Tyr192) at AA range 130-210

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

58 kDa

Formulation

STAM2 (phospho Tyr192) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

STAM2 (phospho Tyr192) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Signal transducing adapter molecule 2 antibody, STAM-2 antibody, Hrs-binding protein antibody

Database links

Human UniProt/Swiss-Prot:O75886;Mouse UniPort/Swiss-Prot: O88811;Rat UniProt/Swiss-Port: Q5XHY7;Human Entrez Gene: 8986;Mouse Entrez Gene: 56324;Rat Entrez Gene: Rn.161793

Protein names

Signal transducing adapter molecule 2 , STAM-2 , Hrs-binding protein

Protein function

Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).

Protein tissue specificity

Ubiquitously expressed.

Protein sequence and domain

The VHS and UIM domains mediate the interaction with ubiquitinated proteins. / The SH3 domain mediates the interaction with USP8. / Contains one Pro-Xaa-Val-Xaa-Leu (PxVxL) motif, which is required for interaction with chromoshadow domains. This motif requires additional residues -7, -6, +4 and +5 of the central Val which contact the chromoshadow domain. / Belongs to the STAM family. / Contains 1 ITAM domain. / Contains 1 SH3 domain. / Contains 1 UIM (ubiquitin-interacting motif) domain. / Contains 1 VHS domain.

Protein post-translational modifications

Phosphorylated in response to IL-2, GM-CSF, EGF and PDGF.

Protein cellular localization

Cytoplasm / Early endosome membrane / Peripheral membrane protein / Cytoplasmic side

Research area

All research areas>Signaling Intermediates>STAM2
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize STAM2 (phospho Tyr192) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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