Rabbit Polyclonal Phospho-STAT4-Y693 antibody (AP0137)

$99.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-STAT4-Y693 antibody (AP0137)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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SLEB11 antibody;
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SCBT cat No:

Name

Rabbit Polyclonal Phospho-STAT4-Y693 antibody

Catalogue No.

AP0137

Reactivity

Human, Mouse, Rat

Immunogen

A phospho specific peptide corresponding to residues surrounding Y693 of human STAT4

Host

Rabbit

Applications

WB, IHC

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

85kDa

Formulation

Phospho-STAT4-Y693 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

SLEB11 antibody;

Protein names

SLEB11;

Protein function

Carries out a dual signal transduction and activation of transcription. Involved in IL12 signaling.

Protein sequence and domain

Belongs to the transcription factor STAT family.; Contains 1 SH2 domain.

Protein post-translational modifications

Tyrosine phosphorylated. Serine phosphorylation is also required for maximal transcriptional activity (By similarity).

Protein cellular localization

Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.

Background

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

Note

AntibodyPlus can customize Phospho-STAT4-Y693 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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